Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid derived in
methionine metabolism. The increased level of Hcy in plasma, hyperhomocysteinemia, is …

Metabolism of excess methionine (Met) to homocysteine (Hcy) by transmethylation is
facilitated by the expression of methionine adenosyltransferase (MAT) I/III and glycine N …

Hydrogen sulfide (H2S) has emerged as a relevant signaling molecule in physiology, taking
its seat as a bona fide gasotransmitter akin to nitric oxide (NO) and carbon monoxide (CO) …

Cystathionine β-synthase (CBS) is responsible for the first enzymatic reaction in the
transsulfuration pathway of sulfur amino acids. The molecular function and mechanism of …

Sulfur contributes significantly to nature chemical diversity and thanks to its particular
features allows fundamental biological reactions that no other element allows. Sulfur natural …

Hydrogen sulfide (H 2 S) is a natural defence against the infections from enveloped RNA
viruses and is likely involved also in Covid 19. It was already shown to inhibit growth and …

Hydrogen sulfide (H 2 S) was previously revealed to inhibit osteoblastic differentiation of
valvular interstitial cells (VICs), a pathological feature in calcific aortic valve disease (CAVD) …

Highlights•This review highlights the prevalence of promiscuity not only in the enzymes that
synthesize hydrogen sulfide, a signaling molecule, but also in the metabolic pathways in …

Regulation of H 2 S homeostasis in humans is poorly understood. Therefore, we assessed
the importance of individual enzymes in synthesis and catabolism of H 2 S by studying …

Neoangiogenesis is a fundamental process which helps to meet energy requirements,
tissue growth, and wound healing. Although previous studies showed that Peroxisome …