Hydrogen peroxide emerged as major redox metabolite operative in redox sensing,
signaling and redox regulation. Generation, transport and capture of H 2 O 2 in biological …

In addition to the roles of endothelial cells (ECs) in physiological processes, ECs actively
participate in both innate and adaptive immune responses. We previously reported that, in …

Rationale: Vascular calcification, the formation of calcium phosphate crystals in the vessel
wall, is mediated by vascular smooth muscle cells (VSMCs). However, the underlying …

As a major cause of morbidity and mortality globally, hypertension remains a serious threat
to global public health. Despite the availability of many antihypertensive medications …

This review focuses on the association between vascular calcification and arterial stiffness,
highlighting the important genetic factors, systemic and local microenvironmental signals …

According to the latest Global Burden of Disease Study data, non-communicable diseases in
general and cardiovascular disease (CVD) in particular are the leading cause of premature …

The development of essential hypertension involves several factors. Vascular dysfunction,
characterized by endothelial dysfunction, low-grade inflammation and structural remodeling …

Various electrochemical biosensors have been developed for direct and real-time recording
of biomolecules released from living cells. However, since these traditional electrodes are …

Mitochondria are crucial bioenergetics powerhouses and biosynthetic hubs within cells,
which can generate and sequester toxic reactive oxygen species (ROS) in response to …

Despite successful therapeutic strategies in the prevention and treatment of arteriosclerosis,
the cardiovascular complications remain a major clinical and societal issue worldwide …