MALAT1: A key regulator in lung cancer pathogenesis and therapeutic targeting

AA Bhat, O Afzal, M Afzal, G Gupta, R Thapa… - … -Research and Practice, 2023 - Elsevier
Lung cancer remains a formidable global health burden, necessitating a comprehensive
understanding of the underlying molecular mechanisms driving its progression. Recently …

From carcinogenesis to therapeutic avenues: lncRNAs and mTOR crosstalk in lung cancer

MS Hussain, ASA Altamimi, M Afzal, I Kazmi… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) have been demonstrated to have a crucial function in the
modulation of the activity of genes, impacting a variety of homeostatic processes involving …

PVT1 lncRNA in lung cancer: A key player in tumorigenesis and therapeutic opportunities

MA Hakami, A Hazazi, FR Khan, O Abdulaziz… - … -Research and Practice, 2023 - Elsevier
The lncRNA PVT1 has emerged as a pivotal component in the intricate landscape of cancer
pathogenesis, particularly in lung cancer. PVT1, situated in the 8q24 chromosomal region …

[HTML][HTML] Non-coding RNA: A key regulator in the Glutathione-GPX4 pathway of ferroptosis

S Hussain, G Gupta, M Shahwan, P Bansal… - Non-coding RNA …, 2024 - Elsevier
Ferroptosis, a form of regulated cell death, has emerged as a crucial process in diverse
pathophysiological states, encompassing cancer, neurodegenerative ailments, and …

MicroRNA-21's role in PTEN suppression and PI3K/AKT activation: Implications for cancer biology

HS Chawra, M Agarwal, A Mishra, SS Chandel… - … -Research and Practice, 2024 - Elsevier
Abstract MicroRNA-21 (miR-21) was recognized as a key figure in the intricate web of tumor
biology, with a prominent role in regulating the PTEN tumor suppressor gene and the …

Osteomyelitis and non-coding RNAS: a new dimension in disease understanding

MS Hussain, NK Shaikh, M Agrawal, M Tufail… - … -Research and Practice, 2024 - Elsevier
Osteomyelitis, a debilitating bone infection, presents considerable clinical challenges due to
its intricate etiology and limited treatment options. Despite strides in surgical and …

Autophagy‐associated non‐coding RNAs: Unraveling their impact on Parkinson's disease pathogenesis

MS Hussain, E Moglad, M Afzal… - CNS Neuroscience …, 2024 - Wiley Online Library
Background Parkinson's disease (PD) is a degenerative neurological condition marked by
the gradual loss of dopaminergic neurons in the substantia nigra pars compacta. The …

Exploring ncRNA-mediated pathways in sepsis-induced pyroptosis

AA Bhat, Y Riadi, M Afzal, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Sepsis, a potentially fatal illness caused by an improper host response to infection, remains
a serious problem in the world of healthcare. In recent years, the role of ncRNA has …

Circular RNAs in the KRAS pathway: Emerging players in cancer progression

MS Hussain, E Moglad, M Afzal, P Bansal… - … -Research and Practice, 2024 - Elsevier
Circular RNAs (circRNAs) have been recognized as key components in the intricate
regulatory network of the KRAS pathway across various cancers. The KRAS pathway, a …

Exploring the oncogenic and tumor-suppressive roles of Circ-ADAM9 in cancer

MS Hussain, E Moglad, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Circular RNAs (circRNAs) constitute a recently identified category of closed continuous loop
RNA transcripts, serving as a subset of competing endogenous RNAs (ceRNAs) with the …