[HTML][HTML] Molecular mechanisms underlying cardiac adaptation to exercise

RB Vega, JP Konhilas, DP Kelly, LA Leinwand - Cell metabolism, 2017 - cell.com
Exercise elicits coordinated multi-organ responses including skeletal muscle, vasculature,
heart, and lung. In the short term, the output of the heart increases to meet the demand of …

Exercise-dependent regulation of the tumour microenvironment

GJ Koelwyn, DF Quail, X Zhang, RM White… - Nature Reviews …, 2017 - nature.com
The integrity and composition of the tumour microenvironment (TME) is highly plastic,
undergoing constant remodelling in response to instructive signals derived from alterations …

Efficacy and Mechanisms of Aerobic Exercise on Cancer Initiation, Progression, and Metastasis: A Critical Systematic Review of In Vivo Preclinical Data

KA Ashcraft, RM Peace, AS Betof, MW Dewhirst… - Cancer research, 2016 - AACR
A major objective of the emerging field of exercise–oncology research is to determine the
efficacy of, and biological mechanisms by which, aerobic exercise affects cancer incidence …

Exercise and the hallmarks of cancer

A Ruiz-Casado, A Martín-Ruiz, LM Pérez, M Provencio… - Trends in cancer, 2017 - cell.com
A wealth of evidence supports an association between regular physical activity (PA) and
decreased risk for cancer and cancer mortality. This is clearly an important issue given the …

[HTML][HTML] Impacts of exercise interventions on different diseases and organ functions in mice

S Guo, Y Huang, Y Zhang, H Huang, S Hong… - Journal of sport and health …, 2020 - Elsevier
Background In recent years, much evidence has emerged to indicate that exercise can
benefit people when performed properly. This review summarizes the exercise interventions …

[HTML][HTML] Exercise and cancer: a position statement from the Spanish Society of Medical Oncology

M Pollán, S Casla-Barrio, J Alfaro, C Esteban… - Clinical and …, 2020 - Springer
Due to improvements in the number of cancer survivors and survival time, there is a growing
interest in healthy behaviors, such as physical activity (PA), and their potential impact on …

Exercise in cancer prevention and anticancer therapy: Efficacy, molecular mechanisms and clinical information

C Zhu, H Ma, A He, Y Li, C He, Y Xia - Cancer letters, 2022 - Elsevier
Modifiable lifestyle factors are the strongest determinants and major preventable causes of
most type of cancer. Exercise has shown many beneficial effects in cancer prevention and …

[HTML][HTML] Exercise in regulation of inflammation-immune axis function in cancer initiation and progression

GJ Koelwyn, E Wennerberg, S Demaria… - … (Williston Park, NY), 2015 - ncbi.nlm.nih.gov
Pharmacologic manipulation of the immune system is emerging as a viable and robust
treatment for some cancer patients. Exercise-induced modulation of the immune system may …

[HTML][HTML] Physical exercise, health, and disease treatment: The role of macrophages

IOM Callegari, GZ Rocha, AG Oliveira - Frontiers in Physiology, 2023 - frontiersin.org
Subclinical inflammation is linked to comorbidities and risk factors, consolidating the
diagnosis of chronic non-communicable diseases, such as insulin resistance …

[HTML][HTML] Differential brain and spinal cord cytokine and BDNF levels in experimental autoimmune encephalomyelitis are modulated by prior and regular exercise

D Bernardes, OC Oliveira-Lima, TV da Silva… - Journal of …, 2013 - Elsevier
The interactions between a prior program of regular exercise and the development of
experimental autoimmune encephalomyelitis (EAE)-mediated responses were evaluated. In …