Aptamer-grafted, cell membrane-coated dendrimer loaded with doxorubicin as a targeted nanosystem against epithelial cellular adhesion molecule (EpCAM) for triple …
The major issue associated with chemotherapeutics is the non-specific distribution,
extended range of toxicity, and low intratumoral accumulation. Targeted therapy using …
extended range of toxicity, and low intratumoral accumulation. Targeted therapy using …
[HTML][HTML] Anti-cancer drug solubility development within a green solvent: Design of novel and robust mathematical models based on artificial intelligence
B Huwaimel, A Alobaida - Molecules, 2022 - mdpi.com
Nowadays, supercritical CO2 (SC-CO2) is known as a promising alternative for
challengeable organic solvents in the pharmaceutical industry. The mathematical prediction …
challengeable organic solvents in the pharmaceutical industry. The mathematical prediction …
[HTML][HTML] Prevention and eradication of biofilm by dendrimers: A possibility still little explored
S Alfei, D Caviglia - Pharmaceutics, 2022 - mdpi.com
Multidrug resistance (MDR) among pathogens and the associated infections represent an
escalating global public health problem that translates into raised mortality and healthcare …
escalating global public health problem that translates into raised mortality and healthcare …
[HTML][HTML] Eradication of Candida albicans Biofilm Viability: In vitro combination therapy of cationic carbosilane dendrons derived from 4-phenylbutyric Acid with AgNO3 …
N Gómez-Casanova, T Lozano-Cruz, J Soliveri… - Journal of Fungi, 2021 - mdpi.com
Candida albicans is a human pathogen of significant clinical relevance. This pathogen is
resistant to different drugs, and most clinical antifungals are not effective against the …
resistant to different drugs, and most clinical antifungals are not effective against the …
[HTML][HTML] Polyamidoamine-stabilized and hyaluronic acid-functionalized gold nanoparticles for cancer therapy
Gold nanoparticles (AuNPs) are versatile nanomaterials that can be used as drug delivery
systems and photothermal agents for cancer therapy. In this study, we developed a novel …
systems and photothermal agents for cancer therapy. In this study, we developed a novel …
Aptamer-functionalized dendrimers for targeted cancer therapy
The concept of cancer-based therapy relies upon the improvement of efficacy with a
reduction in toxicity. The chemotherapeutic agents have shown indiscriminate toxic …
reduction in toxicity. The chemotherapeutic agents have shown indiscriminate toxic …
[PDF][PDF] Dendrimers as modifiers of inorganic nanoparticles for therapeutic delivery in cancer. Pharmaceutics. 2023; 15: 398
M Zenze, A Daniels, M Singh - 2023 - researchgate.net
The formulation of nanoscale systems with well-defined sizes and shapes is of great interest
in applications such as drug and gene delivery, diagnostics and imaging. Dendrimers are …
in applications such as drug and gene delivery, diagnostics and imaging. Dendrimers are …
[HTML][HTML] Anti-biofilm, drug delivery and cytotoxicity properties of dendrimers
CK Ezeh, MEU Dibua - ADMET and DMPK, 2024 - hrcak.srce.hr
Background and purpose Treatments using antimicrobial agents have faced many
difficulties as a result of biofilm formation by pathogenic microorganisms. The biofilm matrix …
difficulties as a result of biofilm formation by pathogenic microorganisms. The biofilm matrix …
Dendrimers: an effective drug delivery and therapeutic approach
The novel hyperbranched, three-dimensional tree-like globular dendritic structures are
gaining popularity in the pharmaceutical field because of their attractive characteristics. The …
gaining popularity in the pharmaceutical field because of their attractive characteristics. The …
Futuristic aspect of nanocarriers on targeted delivery for dementia
S Kumari, JS Bhardwaj, SS Kharavtekar… - … -Based Approaches for …, 2023 - Elsevier
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. Analysis
conducted over the past 20 years has shown that macromolecules accumulating in the brain …
conducted over the past 20 years has shown that macromolecules accumulating in the brain …