Fibroblasts are cells present throughout the human body that are primarily responsible for
the production and maintenance of the extracellular matrix (ECM) within the tissues. They …

Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …

Organized extracellular matrix (ECM), in the form of aligned architectures, is a critical
mediator of directed cancer cell migration by contact guidance, leading to metastasis in solid …

The extracellular microenvironment is an important regulator of cell functions. Numerous
structural cues present in the cellular microenvironment, such as ligand distribution and …

Cell alignment and elongation in the direction of anisotropic and aligned topographies are
key manifestations of cellular contact guidance and are observed in many cell types …

Surface properties are largely responsible for the biological performance of biomedical
devices, suggesting the great necessity of surface modification. Micro-contact printing (μCP) …

Neuroepithelial (NE) organoids with dorsal–ventral patterning provide a useful three‐
dimensional (3D) in vitro model to interrogate neural tube formation during early …

Porous titanium scaffolds fabricated by powder bed fusion additive manufacturing
techniques have been widely adopted for orthopedic and bone tissue engineering …

The extracellular matrix (ECM) of the tissue organ exhibits a topography from the nano to
micrometer range, and the design of scaffolds has been inspired by the host environment …

The substratum topography of both natural and synthetic materials is a prominent regulator
of cell behaviors including adhesion, migration, matrix fibrillogenesis, and cell phenotype …