Solubility enhancement of antidiabetic drugs using a co‐crystallization approach

E Batisai - ChemistryOpen, 2021 - Wiley Online Library
The co‐crystallization approach has been used to enhance specific desirable properties of
active pharmaceutical ingredients (APIs) such as solubility, dissolution rate, and stability …

Can machine learning predict drug nanocrystals?

Y He, Z Ye, X Liu, Z Wei, F Qiu, HF Li, Y Zheng… - Journal of Controlled …, 2020 - Elsevier
Nanocrystals have exhibited great advantage for enhancing the dissolution rate of water
insoluble drugs due to the reduced size to nanoscale. However, current pharmaceutical …

Exploring role of probiotics and Ganoderma lucidum extract powder as solid carriers to solidify liquid self-nanoemulsifying delivery systems loaded with curcumin

R Khursheed, SK Singh, S Wadhwa, M Gulati… - Carbohydrate …, 2020 - Elsevier
Solid self-nanoemulsifying drug delivery system (S-SENDDS) containing Curcumin (CRM)
were prepared using combination of Ganoderma lucidum extract powder (GLEP) and …

Development of guar gum-pectin-based colon targeted solid self-nanoemulsifying drug delivery system of xanthohumol

M Hanmantrao, S Chaterjee, R Kumar, S Vishwas… - Pharmaceutics, 2022 - mdpi.com
Present study deciphers development of oral polysaccharide-based colon targeted solid self-
nanoemulsifying drug delivery system (S-SNEDDS) of xanthohumol (XH). Several studies …

Levofloxacin cocrystal/salt with phthalimide and caffeic acid as promising solid-state approach to improve antimicrobial efficiency

NU Islam, MN Umar, E Khan, FA Al-Joufi, SN Abed… - Antibiotics, 2022 - mdpi.com
To overcome the issue of multidrug resistant (MDR) microbes, the exploration of ways to
improve the antimicrobial efficiency of existing antibiotics is one of the promising …

Formulation and evaluation of buccal films of piroxicam co-crystals

A Ammanage, P Rodriques, A Kempwade… - Future Journal of …, 2020 - Springer
Background The aim of the present study was to enhance the solubility of piroxicam (BCS
class II drug) using co-crystallization technique and formulate the buccal films of selected co …

Metolazone co-crystals-loaded oral fast dissolving films: Design, optimization, and in vivo evaluation

MS Mohamed, AA El-Shenawy, EA Mahmoud… - Journal of Drug Delivery …, 2023 - Elsevier
This study aimed to formulate and optimize metolazone (MLZ) co-crystals incorporating fast-
dissolving films (OFDFs) as an agreeable oral formulation for improving the bioavailability of …

[PDF][PDF] Design and preparation of zaltoprofen-nicotinamide pharmaceutical cocrystals via liquid assisted grinding method

P Panzade, G Shendarkar - Indian J. Pharm. Educ. Res, 2019 - academia.edu
Introduction: Pharmaceutical cocrystal is an endowed approach to augment solubility and
dissolution of drugs with limited aqueous solubility. Zaltoprofen is a nonsteroidal anti …

Synthesis, powder diffraction pattern, crystal structure determination of the pharmaceutical co-crystal of levetiracetam and 3, 5-dinitrosalicylic acid

L Shi, Z Chen, H Kafafy, Z Zhang, G Zhu, J Yao… - Powder …, 2023 - cambridge.org
(S)-α-Ethyl-2-oxo-1-pyrrolidineacetamide (trade name levetiracetam), a derivative of
piracetam, is used clinically as an add-on treatment for partial-onset seizures. In this study …

The physico-chemical properties of glipizide: new findings

G Bruni, I Ghione, V Berbenni, A Cardini, D Capsoni… - Molecules, 2021 - mdpi.com
The present work is a concrete example of how physico-chemical studies, if performed in
depth, are crucial to understand the behavior of pharmaceutical solids and constitute a solid …