Obstructive sleep apnoea heterogeneity and cardiovascular disease

S Redline, A Azarbarzin, Y Peker - Nature Reviews Cardiology, 2023 - nature.com
Obstructive sleep apnoea (OSA), characterized by recurrent periods of upper airway
obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease …

Large variability in definitions of sleep apnea indices used in clinical studies

EM Balk, GP Adam, CM D'Ambrosio - Journal of Clinical Sleep …, 2024 - jcsm.aasm.org
Study Objectives: We explored the variability of sleep apnea indices and definitions of
obstructive sleep apnea in clinical studies of continuous positive airway pressure. Methods …

Long-term health outcomes for patients with obstructive sleep apnea: placing the Agency for Healthcare Research and Quality report in context—a multisociety …

SP Patil, ME Billings, G Bourjeily, NA Collop… - Journal of Clinical …, 2024 - jcsm.aasm.org
This multisociety commentary critically examines the Agency for Healthcare Research and
Quality (AHRQ) final report and systematic review on long-term health outcomes in …

[HTML][HTML] New insights and potential clinical implications of the odds ratio product

M Younes - Frontiers in Neurology, 2023 - frontiersin.org
The odds ratio product (ORP) is a continuous metric of sleep depth that ranges from 0 (very
deep sleep) to 2. 5 (full wakefulness). Its advantage over the conventional method …

Strategies to assess the effect of continuous positive airway pressure on long-term clinically important outcomes among patients with symptomatic obstructive sleep …

LM Donovan, CM Hoyos, RJ Kimoff… - Annals of the …, 2023 - atsjournals.org
Continuous positive airway pressure (CPAP) is the first-line treatment for obstructive sleep
apnea (OSA). Although CPAP improves symptoms (eg, daytime sleepiness), there is a lack …

Unmasking heterogeneity of sleep apnea

AI Pack - Sleep Medicine Clinics, 2023 - sleep.theclinics.com
Obstructive sleep apnea (OSA) is a common disorder. 1 There is growing evidence that
there is substantial heterogeneity among patients with the same apparent severity of …

CPAP therapy for obstructive sleep apnoea: are the right questions being asked?

DJ Gottlieb - European Respiratory Journal, 2023 - Eur Respiratory Soc
Extract The recently published technology assessment of continuous positive airway
pressure (CPAP), prepared for the Agency for Healthcare Research and Quality (AHRQ) of …

The individual and societal prices of non-adherence to continuous positive airway pressure, contributors, and strategies for improvement

M Mendelson, J Duval, F Bettega… - Expert Review of …, 2023 - Taylor & Francis
Introduction Continuous positive airway pressure (CPAP) is the first-line therapy for
obstructive sleep apnea (OSA). CPAP is highly effective for improving symptoms and quality …

CPAP therapy for obstructive sleep apnoea: persisting challenges in outcome assessment

WT McNicholas, ES Arnardottir… - European …, 2023 - Eur Respiratory Soc
Extract A recently published report prepared for the Agency for Healthcare Research and
Quality (AHRQ) of the US Department of Health and Human Services concluded that the …

Loop Gain as a Predictor of Blood Pressure Response in Patients Treated for Obstructive Sleep Apnea: Secondary Analysis of a Clinical Trial

CN Schmickl, JE Orr, SA Sands, RM Alex… - Annals of the …, 2024 - atsjournals.org
Rationale: Randomized trials have shown inconsistent cardiovascular benefits from
obstructive sleep apnea (OSA) therapy. Intermittent hypoxemia can increase both …