The involvement of glucose and lipid metabolism alteration in rheumatoid arthritis and its clinical implication

TT Luo, YJ Wu, Q Yin, WG Chen… - Journal of Inflammation …, 2023 - Taylor & Francis
Obviously, immune cells like T cells and macrophages play a major role in rheumatoid
arthritis (RA). On one hand, the breakdown of immune homeostasis directly induces …

[HTML][HTML] Metabolic targeting of cancer associated fibroblasts overcomes T-cell exclusion and chemoresistance in soft-tissue sarcomas

MT Broz, EY Ko, K Ishaya, J Xiao, M De Simone… - Nature …, 2024 - nature.com
T cell-based immunotherapies have exhibited promising outcomes in tumor control;
however, their efficacy is limited in immune-excluded tumors. Cancer-associated fibroblasts …

Role and regulation of GLUT1/3 during oral cancer progression and therapy resistance

A Kumari, A Jha, A Tiwari, N Nath, A Kumar… - Archives of Oral …, 2023 - Elsevier
Objective This study aimed to determine whether glucose transporter-1/3 (GLUT1/3)
increased expression could contribute to oral tumor severity. Furthermore, this study …

Glycolysis: A fork in the path of normal and pathological pregnancy

R Gou, X Zhang - The FASEB Journal, 2023 - Wiley Online Library
Glucose metabolism is vital to the survival of living organisms. Since the discovery of the
Warburg effect in the 1920s, glycolysis has become a major research area in the field of …

Systemic Reduction of Glut1 Normalizes Retinal Dysfunction, Inflammation, and Oxidative Stress in the Retina of Spontaneous Type 2 Diabetic Mice

JJ Aiello, MC Bogart, WT Chan, NC Holoman… - The American Journal of …, 2023 - Elsevier
Defects in the light-evoked responses of the retina occur early in the sequalae of diabetic
retinopathy (DR). These defects, identified through the electroretinogram (ERG), represent …

[HTML][HTML] Aberrantly Glycosylated GLUT1 as a Poor Prognosis Marker in Aggressive Bladder Cancer

E Ferreira, D Ferreira, M Relvas-Santos… - International Journal of …, 2024 - mdpi.com
Muscle-invasive bladder cancer (MIBC) remains a pressing health concern due to
conventional treatment failure and significant molecular heterogeneity, hampering the …

[HTML][HTML] Carbohydrate effect of novel arene Ru (II) phenanthroline-glycoconjugates on metastatic biological processes

E de la Torre-Rubio, L Muñoz-Moreno, AM Bajo… - Journal of Inorganic …, 2023 - Elsevier
Novel water-soluble half-sandwich ruthenium (II) polypyridyl-glycoconjugates [Ru (p-
cymene) Cl {N-(1, 10-phenanthroline-5-yl)-β-glycopyranosylamine}][Cl](glycopyranosyl= d …

Identification of starvation-mimetic bioactive phytocomponent from Withania somnifera using in-silico molecular modelling and flow cytometry-based analysis for the …

D Pradhan, P Biswasroy, S Kulkarni… - Journal of …, 2024 - Taylor & Francis
Multidrug resistance episodes in malaria increased from 3.9% to 20% from 2015 to 2019.
Synchronizing the clinical manifestation in chronological sequence led to a unique …

Correlations between class I glucose transporter expression patterns and clinical outcomes in non‐small cell lung cancer

Y Nakanishi, M Iwai, Y Hirotani, R Kato… - Thoracic …, 2023 - Wiley Online Library
Abstract Background Glucose transporters (GLUTs) are highly expressed in various cancers.
However, the implications of these variable expression patterns are unclear. This study …

[HTML][HTML] SUV max as Predictor of Metastatic Disease on 18 F-FDG PET-CT in Hepatocellular Carcinoma

W Ashfaq, K Rehman, A Shahid, MN Younis - Journal of the College of …, 2024 - jcpsp.pk
Objective: To ascertain the utility of maximum standardised uptake value (SUV max) in 18 F-
FDG PET-CT in predicting metastatic disease burden in hepatocellular carcinoma (HCC) …