Body‐wide chimerism and mosaicism are predominant causes of naturally occurring ABO discrepancies

EM Dauber, OA Haas, K Nebral… - British Journal of …, 2024 - Wiley Online Library
Routine ABO blood group typing of apparently healthy individuals sporadically uncovers
unexplained mixed‐field reactions. Such blood group discrepancies can either result from a …

Social, Behavioral, and Clinical Risk Factors Are Associated with Clonal Hematopoiesis

CD Young, AK Hubbard, PF Saint-Maurice… - Cancer Epidemiology …, 2024 - aacrjournals.org
Background: Risk factors including smoking, alcohol intake, physical activity (PA), and sleep
patterns have been associated with cancer risk. Clonal hematopoiesis (CH), including …

[HTML][HTML] 中国10 个地区成年人外周血嵌合染色体变异的流行病学分布特征

宋明钰, 赵禹碹, 韩雨廷, 吕筠, 余灿清, 裴培… - 中华流行病学 …, 2023 - html.rhhz.net
目的描述外周血嵌合染色体变异(mCA) 在我国10 个地区30~ 79 岁自然人群的流行病学分布
特征. 方法纳入中国慢性病前瞻性研究(CKB) 10 个项目地区中已有基线数据(人口学特征 …

Multi-ancestry genome-wide association meta-analysis of mosaic loss of chromosome Y in the Million Veteran Program identifies 167 novel loci

M Francis, BR Gorman, TB Bigdeli, G Genovese… - medRxiv, 2024 - medrxiv.org
Mosaic loss of chromosome Y (mLOY) is a common somatic mutation in leukocytes of older
males. mLOY was detected in 126,108 participants of the Million Veteran Program: 106,054 …