Engineered scaffolds produced by electrospinning of biodegradable polymers offer a 3D,
nanofibrous environment with controllable structural, chemical, and mechanical properties …

Engineering of three-dimensional (3D) tissues is a promising approach for restoring
diseased or dysfunctional myocardium with a functional replacement. However, a major …

Early surgical resection and chemotherapy of bone cancer are commonly used in the
treatment of bone tumor, but it is still highly challenging to prevent recurrence and fill the …

Cell replacement therapy with human pluripotent stem cell-derived neurons has the
potential to ameliorate neurodegenerative dysfunction and central nervous system injuries …

Metastasis is clinically the most challenging and lethal aspect of breast cancer. While animal-
based xenograft models are expensive and time-consuming, conventional two-dimensional …

Over the past few decades, a variety of different reagents for stem cell maintenance and
differentiation have been commercialized. These reagents share a common goal in …

Both human pluripotent stem cells (hPSCs) from embryonic stem cells (hESCs) and induced
pluripotent stem cells (hiPSCs) have the potential ability to differentiate into many different …

This review describes recent developments regarding the use of natural and synthetic
polymers to support the propagation of human pluripotent stem cells (hPSCs), human …

Clinical use of human pluripotent stem cells (hPSCs) is hampered by the technical
limitations of their expansion. Here, we developed a chemically synthetic culture substrate …

The fate decisions of human pluripotent stem (hPS) cells are governed by soluble and
insoluble signals from the microenvironment. Many hPS cell differentiation protocols use …