Targeting Akt/CREB/BDNF signaling pathway by ginsenosides in neurodegenerative diseases: A mechanistic approach
Neurodegenerative diseases (NDDs) are leading causes of death and morbidity in the
elderly worldwide. From the mechanistic/pathological view, oxidative stress, inflammation …
elderly worldwide. From the mechanistic/pathological view, oxidative stress, inflammation …
[HTML][HTML] Ursolic acid and its derivatives as bioactive agents
Non-communicable diseases (NCDs) such as cancer, diabetes, and chronic respiratory and
cardiovascular diseases continue to be threatening and deadly to human kind. Resistance …
cardiovascular diseases continue to be threatening and deadly to human kind. Resistance …
A narrative review of the antitumor activity of monoterpenes from essential oils: An update
TQ Machado, ACC Da Fonseca… - BioMed research …, 2022 - Wiley Online Library
Monoterpenes are a group of natural products that have been widely studied due to their
therapeutic potential against various pathologies. These compounds are abundant in the …
therapeutic potential against various pathologies. These compounds are abundant in the …
[HTML][HTML] Bioactive Secondary Metabolites of the Genus Diaporthe and Anamorph Phomopsis from Terrestrial and Marine Habitats and Endophytes: 2010–2019
TC Xu, YH Lu, JF Wang, ZQ Song, YG Hou, SS Liu… - Microorganisms, 2021 - mdpi.com
The genus Diaporthe and its anamorph Phomopsis are distributed worldwide in many
ecosystems. They are regarded as potential sources for producing diverse bioactive …
ecosystems. They are regarded as potential sources for producing diverse bioactive …
Selected plant triterpenoids and their amide derivatives in cancer treatment: A review
Z Özdemir, Z Wimmer - Phytochemistry, 2022 - Elsevier
Medicinal plants have been used to treat different diseases throughout the human history
namely in traditional medicine. Most of the plants mentioned in this review article belong …
namely in traditional medicine. Most of the plants mentioned in this review article belong …
[HTML][HTML] A review on the sources, structures, and pharmacological activities of lucidenic acids
C Zheng, P Rangsinth, PHT Shiu, W Wang, R Li, J Li… - Molecules, 2023 - mdpi.com
Ganoderma lucidum has long been used as a multi-purpose plant and functional food. The
pharmacological properties of G. lucidum are primarily attributed to its polysaccharides and …
pharmacological properties of G. lucidum are primarily attributed to its polysaccharides and …
Ursolic acid: An overview on its cytotoxic activities against breast and colorectal cancer cells
Ursolic acid (UA) is a pentacyclic triterpene of the ursane type. As a common chemical
constituent among species of the family Lamiaceae, UA possesses a broad spectrum of …
constituent among species of the family Lamiaceae, UA possesses a broad spectrum of …
Recent progress on betulinic acid and its derivatives as antitumor agents: A mini review
Y Zhong, N Liang, LIU Yang, MS Cheng - Chinese Journal of Natural …, 2021 - Elsevier
Natural products are one of the important sources for the discovery of new drugs. Betulinic
acid (BA), a pentacyclic triterpenoid widely distributed in the plant kingdom, exhibits …
acid (BA), a pentacyclic triterpenoid widely distributed in the plant kingdom, exhibits …
[HTML][HTML] Ursolic and oleanolic acids induce mitophagy in A549 human lung cancer cells
NS Castrejón-Jiménez, K Leyva-Paredes… - Molecules, 2019 - mdpi.com
Ursolic and oleanolic acids are natural isomeric triterpenes known for their anticancer
activity. Here, we investigated the effect of triterpenes on the viability of A549 human lung …
activity. Here, we investigated the effect of triterpenes on the viability of A549 human lung …
[HTML][HTML] Biotransformation of oleanane and ursane triterpenic acids
NA Luchnikova, VV Grishko, IB Ivshina - Molecules, 2020 - mdpi.com
Oleanane and ursane pentacyclic triterpenoids are secondary metabolites of plants found in
various climatic zones and regions. This group of compounds is highly attractive due to their …
various climatic zones and regions. This group of compounds is highly attractive due to their …