Thecells were obtained from Dainippon Pharmaceutical Co., Ltd.(Osaka, Japan)
andcultured at 37 Cin 5% CO2humidified atmosphere in a Falcon plastic culture flask …

We have recently characterized the promoter region of the rabbit embryonic smooth muscle
myosin heavy chain (SMemb/NMHC-B) gene and identified the 15-bp sequence, designated …

Objective: Thickened atherosclerotic plaques are prone to be hypoxic because of poor
perfusion. In this study, we tested (a) whether reactive oxygen species (ROS) and c-Src play …

Migration of medial smooth muscle cells (SMC) into the intima is important in intimal
thickening of atherosclerotic tissues. To study the functions of three isoforms of platelet …

h2-Calponin is found in both smooth muscle and nonmuscle cells, and its function remains
to be established. Western blots with specific monoclonal antibodies detected significant …

Calponin is an extensively studied actin-binding protein, but its function is not well
understood. Among three isoforms of calponin, h2-calponin is found in both smooth muscle …

We have recently demonstrated that a developmentally regulated zinc finger protein, basic
transcription regulatory element binding protein 2 (BTEB2), is induced in neointimal smooth …

Transforming growth factor (TGF)-β plays a major role in the development of vascular
diseases. Despite the pleiotropic effects of TGF-β on vascular smooth muscle cells (VSMCs) …

Using the specific antibodies pLC1 and pLC2 for mono-and diphosphorylated 20-kDa
myosin light chain (MLC20) at Ser19 and at both Thr18 and Ser19, respectively, we …

SM22α, also named transgelin, is an actin filament-associated protein in smooth muscle and
fibroblasts. Three decades after its discovery, the biological function of SM22α remains …