The role of damage associated molecular pattern molecules (DAMPs) and permeability of the blood-brain barrier in depression and neuroinflammation

MF Serna-Rodríguez, S Bernal-Vega… - Journal of …, 2022 - Elsevier
Depression is a heterogeneous mental disorder characterized by feelings of sadness and
loss of interest that render the subject unable to handle basic daily activities such as …

[HTML][HTML] Emerging exosomes and exosomal MiRNAs in spinal cord injury

J Feng, Y Zhang, Z Zhu, C Gu, A Waqas… - Frontiers in Cell and …, 2021 - frontiersin.org
Acute spinal cord injury (SCI) is a serious traumatic event to the spinal cord with
considerable morbidity and mortality. This injury leads to short-and long-term variations in …

[HTML][HTML] Military traumatic brain injury: a challenge straddling neurology and psychiatry

LZ Kong, RL Zhang, SH Hu, JB Lai - Military medical research, 2022 - Springer
Military psychiatry, a new subcategory of psychiatry, has become an invaluable, intangible
effect of the war. In this review, we begin by examining related military research …

Structural alignment guides oriented migration and differentiation of endogenous neural stem cells for neurogenesis in brain injury treatment

Y Chai, H Zhao, S Yang, X Gao, Z Cao, J Lu, Q Sun… - Biomaterials, 2022 - Elsevier
Radial glia (RG) cells that align in parallel in the embryonic brain are found to be able to
guide the directed migration of neurons in response to brain injury. Therefore, biomaterials …

[HTML][HTML] In vivo methods for imaging blood–brain barrier function and dysfunction

WJ Harris, MC Asselin, R Hinz, LM Parkes… - European Journal of …, 2023 - Springer
The blood–brain barrier (BBB) is the interface between the central nervous system and
systemic circulation. It tightly regulates what enters and is removed from the brain …

Elevated PDGF‐BB from Bone Impairs Hippocampal Vasculature by Inducing PDGFRβ Shedding from Pericytes

G Liu, J Wang, Z Wei, CL Fang, K Shen… - Advanced …, 2023 - Wiley Online Library
Evidence suggests a unique association between bone aging and neurodegenerative/
cerebrovascular disorders. However, the mechanisms underlying bone‐brain interplay …

[HTML][HTML] Traumatic brain injury: Ultrastructural features in neuronal ferroptosis, glial cell activation and polarization, and blood–brain barrier breakdown

D Qin, J Wang, A Le, TJ Wang, X Chen, J Wang - Cells, 2021 - mdpi.com
The secondary injury process after traumatic brain injury (TBI) results in motor dysfunction,
cognitive and emotional impairment, and poor outcomes. These injury cascades include …

[HTML][HTML] Blood-brain barrier dysfunction in CNS disorders and putative therapeutic targets: an overview

SR Archie, A Al Shoyaib, L Cucullo - Pharmaceutics, 2021 - mdpi.com
The blood-brain barrier (BBB) is a fundamental component of the central nervous system
(CNS). Its functional and structural integrity is vital to maintain the homeostasis of the brain …

[HTML][HTML] Blood–Brain Barrier Disruption and Its Involvement in Neurodevelopmental and Neurodegenerative Disorders

A Aragón-González, PJ Shaw, L Ferraiuolo - International Journal of …, 2022 - mdpi.com
The blood–brain barrier (BBB) is a highly specialized and dynamic compartment which
regulates the uptake of molecules and solutes from the blood. The relevance of the …

Autophagy and apoptosis in acute brain injuries: from mechanism to treatment

C He, Y Xu, J Sun, L Li, JH Zhang… - Antioxidants & Redox …, 2023 - liebertpub.com
Significance: Autophagy and apoptosis are two important cellular mechanisms behind brain
injuries, which are severe clinical situations with increasing incidences worldwide. To …