CONTEXT: Kidney cancer is among the 10 most frequently occurring cancers in Western
communities. Globally, about 270 000 cases of kidney cancer are diagnosed yearly and 116 …

Abstract Anti-programmed death (PD)-1 agents pembrolizumab and nivolumab have
recently obtained enthusiastic results in terms of progression-free survival (PFS), overall …

Background Renal cell carcinoma (RCC) is the most common type of kidney cancer.
Studying the pathogenesis of RCC is particularly important, because it could provide a direct …

Renal cell carcinoma is the 14th most common cancer worldwide. It is a heterogeneous
group of histopathological entities, of which the most common is clear cell renal cell …

Background The aim of this study was to compare survival of resected and unresected
patients in a large cohort of patients with metastases to the pancreas from renal cell …

Purpose Aim of this study was to investigate for the presence of existing prognostic factors in
patients with bone metastases (BMs) from RCC since bone represents an unfavorable site of …

Personalized medicine involves the selection of the safest and most effective
pharmacological treatment based on the molecular characteristics of the patient. In the case …

Significant advances in molecular medicine have made renal cell carcinoma (RCC) the
prototype solid organ malignancy for targeted medical cancer treatment. Theseis new …

Background Bone metastasis represents an increasing clinical problem in advanced renal
cell carcinoma (RCC) as disease-related survival improves. There are few data on the …

Background The system L amino acid transporter (LAT) has an important role in the
transport of various amino acids, and there have been reports about the relation of this …