Pharmacological receptors on blood-platelets

SMO Hourani, NJ Cusack - Pharmacological reviews, 1991 - openresearch.surrey.ac.uk
Science & Technology Life Sciences & Biomedicine Pharmacology & Pharmacy
PHARMACOLOGY & PHARMACY ACTIVATING FACTOR PAF INTACT HUMAN …

Platelet-activating factor (PAF): implications for coronary heart and vascular diseases

AM Evangelou - Prostaglandins, leukotrienes and essential fatty acids, 1994 - Elsevier
Platelet activating factor (PAF) research, could be divided into three periods. The first, which
could be named the 'pioneer period', started in the sixties, when a reaction involving …

Choline-linked phosphoglycerides: a source of phosphatidic acid and diglycerides in stimulated neutrophils

DE Agwu, LC McPhail, MC Chabot, LW Daniel… - Journal of Biological …, 1989 - Elsevier
Stimulation of human polymorphonuclear leukocytes (PMN) may result in the metabolism of
phospholipids other than phosphoinositides to generate second-messenger intermediary …

[HTML][HTML] A novel mechanism of diglyceride formation. 12-O-tetradecanoylphorbol-13-acetate stimulates the cyclic breakdown and resynthesis of phosphatidylcholine.

LW Daniel, M Waite, RL Wykle - Journal of Biological Chemistry, 1986 - Elsevier
12-O-Tetradecanoylphorbol-13-acetate (TPA) treatment of Madin-Darby canine kidney cells
resulted in an increased incorporation of 32Pi and [methyl-3H] choline into choline …

Phosphatidic acid as a second messenger in human polymorphonuclear leukocytes. Effects on activation of NADPH oxidase.

DE Agwu, LC McPhail, S Sozzani… - The Journal of …, 1991 - Am Soc Clin Investig
Receptor-mediated agonists, such as FMLP, induce an early, phospholipase D (PLD)-
mediated accumulation of phosphatidic acid (PA) which may play a role in the activation of …

Strategies for the synthesis of glycerophospholipids

F Paltauf, A Hermetter - Progress in lipid research, 1994 - Elsevier
Presently we are facing an increasing demand for chemically defined glycerophospholipids
that are used in membrane and lipoprotein research, in liposome technology or as bioactive …

Binding and metabolism of platelet-activating factor by human neutrophils.

JT O'Flaherty, JR Surles, J Redman… - The Journal of …, 1986 - Am Soc Clin Investig
Human polymorphonuclear neutrophils rapidly incorporated radiolabeled platelet-activating
factor, 1-O-[hexadecyl-9, 10-3H2]-2-acetyl-sn-glycero-3-phosphocholine ([3H] PAF), and …

[HTML][HTML] Tumor necrosis factor alpha priming of phospholipase D in human neutrophils: correlation between phosphatidic acid production and superoxide generation

SA Bauldry, DA Bass, SL Cousart, CE McCall - Journal of Biological …, 1991 - Elsevier
Tumor necrosis factor alpha (TNF) primes human neutrophils (PMN) for enhanced
superoxide (O2-) production if cells are subsequently stimulated with the chemotactic …

Primed stimulation of isolated perfused rabbit lung by endotoxin and platelet activating factor induces enhanced production of thromboxane and lung injury.

WL Salzer, CE McCall - The Journal of clinical investigation, 1990 - Am Soc Clin Investig
Bacterial sepsis often precedes the development of the adult respiratory distress syndrome
(ARDS) and bacterial endotoxin (LPS) produces a syndrome similar to ARDS when infused …

[HTML][HTML] The final step in the de novo biosynthesis of platelet-activating factor. Properties of a unique CDP-choline: 1-alkyl-2-acetyl-sn-glycerol choline …

DS Woodard, TC Lee, F Snyder - Journal of Biological Chemistry, 1987 - Elsevier
Final steps in the synthesis of platelet activating factor (PAF) occur via two enzymatic
reactions: the acetylation of 1-alkyl-2-lyso-sn-glycero-3-phosphocholine by a specific …