Glycoengineering of therapeutic antibodies with small molecule inhibitors
S Li, AJ McCraw, RA Gardner, DIR Spencer… - Antibodies, 2021 - mdpi.com
Monoclonal antibodies (mAbs) are one of the cornerstones of modern medicine, across an
increasing range of therapeutic areas. All therapeutic mAbs are glycoproteins, ie, their …
increasing range of therapeutic areas. All therapeutic mAbs are glycoproteins, ie, their …
Recent advances on glycosyltransferases involved in the biosynthesis of the proteoglycan linkage region
Proteoglycans (PGs) are an essential family of glycoproteins, which can play roles in many
important biological events including cell proliferation, cancer development, and pathogen …
important biological events including cell proliferation, cancer development, and pathogen …
Aberration of Serum and Tissue N-Glycans in Mouse β1,4-GalT1 Y286L Mutant Variants
R Cao, TC Zhang, YR Chen, C Cao, H Chen… - Glycoconjugate …, 2020 - Springer
Abstract β1, 4-GalT1 is a type II membrane glycosyltransferase. It catalyzes the production of
lactose in the lactating mammary gland and is supposedly also involved in the …
lactose in the lactating mammary gland and is supposedly also involved in the …
[PDF][PDF] Development of glycosyltransferase inhibitors for the glycoengineering of therapeutic antibodies
S Li - 2024 - kclpure.kcl.ac.uk
First and foremost, I would like to sincerely thank my supervisors Prof. Gerd Wagner and
Prof. Sophia Karagiannis for their invaluable support, guidance and expertise. I would also …
Prof. Sophia Karagiannis for their invaluable support, guidance and expertise. I would also …