Neurometabolic characteristics in the anterior cingulate gyrus of Alzheimer's disease patients with depression: a 1H magnetic resonance spectroscopy study

Z Guo, J Zhang, X Liu, H Hou, Y Cao, F Wei, J Li… - BMC psychiatry, 2015 - Springer
Background Depression is a common comorbid psychiatric symptom in patients with
Alzheimer's disease (AD), and the prevalence of depression is higher among people with …

The use of antidepressant medication before and after the diagnosis of amyotrophic lateral sclerosis: a population-based cohort study

FE Pisa, G Logroscino, A Casetta, L Cecotti… - …, 2015 - karger.com
Background: The prevalent use of antidepressants (ATDs) in patients with Amyotrophic
Lateral Sclerosis (ALS) varies across cross-sectional and clinic-based published studies …

The relationship between major depressive disorder and dementia: A bidirectional two-sample Mendelian randomization study

Y Hu, Y Zou, M Zhang, J Yan, Y Zheng… - Journal of Affective …, 2024 - Elsevier
Background Major depressive disorder (MDD) and dementia psychiatric and neurological
diseases that are clinically widespread, but whether there is a causal link between them is …

Prophylactic effect of physical exercise on Aβ1-40-induced depressive-like behavior and gut dysfunction in mice

JM Rosa, FL Pazini, A Camargo, IAV Wolin… - Behavioural Brain …, 2020 - Elsevier
Alzheimer's disease (AD) is a prevalent neurodegenerative disease that is highly comorbid
with depression. Gut dysfunction has been proposed as a possible risk factor for both clinical …

Chronic pain exacerbates memory impairment and pathology of Aβ and tau by upregulating IL-1β and p-65 signaling in a mouse model of Alzheimer's disease

W Wang, W Zheng, X Du, S Chen, Y Chen, H Wang… - Brain Research, 2024 - Elsevier
Background Chronic pain is linked to cognitive impairment; however, the underlying
mechanisms remain unclear. In the present study, we examined these mechanisms in a well …

Trauma and depressive symptomatology in middle-aged persons at high risk of dementia: the PREVENT Dementia Study

K Ritchie, I Carrière, S Gregory… - Journal of Neurology …, 2021 - jnnp.bmj.com
Objective Depression and trauma are associated with changes in brain regions implicated in
Alzheimer's disease. The present study examined associations between childhood trauma …

Depressive symptoms and CSF Alzheimer's disease biomarkers in relation to clinical symptom onset of mild cognitive impairment

CK Chan, A Soldan, C Pettigrew… - Alzheimer's & …, 2020 - Wiley Online Library
Introduction We sought to examine whether depressive symptoms and level of Alzheimer's
disease (AD) pathology are independently or interactively associated with the risk of …

Regional coherence changes in Alzheimer's disease patients with depressive symptoms: a resting-state functional MRI study

Z Guo, X Liu, X Jia, H Hou, Y Cao, F Wei… - Journal of …, 2015 - content.iospress.com
Alzheimer's disease (AD) is characterized by progressive cognitive decline along with
neuropsychiatric symptoms including depression and psychosis. Depression is a common …

Parallel molecular alteration between Alzheimer's disease and major depressive disorder in the human brain dorsolateral prefrontal cortex: An insight from gene …

S Rastad, N Barjaste, H Lanjanian, A Moeini… - Genes & Genetic …, 2022 - jstage.jst.go.jp
Alzheimer's disease (AD) and major depressive disorder (MDD) are comorbid
neuropsychiatric disorders that are among the leading causes of long-term disability …

Anosognosia and its relation to psychiatric symptoms in early-onset Alzheimer disease

B Yoon, YS Shim, YJ Hong, SH Choi… - Journal of Geriatric …, 2017 - journals.sagepub.com
Background: We investigated differences in the prevalence of anosognosia and
neuropsychiatric symptoms (NPSs) characteristics according to disease severity in patients …