Primary immunodeficiencies (PIDs) are inherited disorders in which one or several
components of immune system are decreased, missing, or of non-appropriate function …

Common variable immunodeficiency (CVID) refers to a grouping of antibody deficiencies
that lack a more specific genetic or phenotypic classification. It is the immunodeficiency …

Background Common variable immunodeficiency (CVID) is a heterogeneous disorder
characterized by recurrent infections and defective immunoglobulin production. Methods …

Primary humoral immune deficiencies are characterized by limited antibody responses
secondary to either impaired B-lymphocyte development or B-cell responses to T …

Chronic infection with norovirus is emerging as a significant risk for patients with
immunodeficiency–either primary or secondary to therapeutic immunosuppression. Patients …

Background Diagnostic delay in common variable immunodeficiency disorders (CVID) is
considerable. There is no generally accepted symptom-recognition framework for its early …

Introduction: Common variable immunodeficiency (CVID) comprises a large heterogeneous
group of patients with primary antibody deficiency. Areas covered: The affected patients are …

Abstract Colonel Ogden Bruton reported X-Linked Agammaglobulinaemia in 1952 and
treated the child with replacement immunoglobulin therapy. Over 60 years later, the …

Common variable immunodeficiency (CVID) is the most common symptomatic primary
antibody immunodeficiency, characterized by reduced serum levels of IgG, IgA, and/or IgM …

Background: Common variable immunodeficiency (CVID) is the most common clinically
significant primary immunodeficiency (PID) disorder characterized by variable clinical …