Recent discovery of tyrosinase inhibitors in traditional Chinese medicines and screening methods

J Li, C Li, X Peng, S Li, B Liu, C Chu - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Tyrosinase, the key rate-limiting enzyme for
melanogenesis, is one of the main targets for skin senescence and some pigmented skin …

Strategies for capillary electrophoresis: method development and validation for pharmaceutical and biological applications—updated and completely revised edition

F Krebs, H Zagst, M Stein, R Ratih, R Minkner… - …, 2023 - Wiley Online Library
This review is in support of the development of selective, precise, fast, and validated
capillary electrophoresis (CE) methods. It follows up a similar article from 1998, Wätzig H …

Screening of lactate dehydrogenase inhibitor from bioactive compounds in natural products by electrophoretically mediated microanalysis

W Li, X Cui, Z Chen - Journal of Chromatography A, 2021 - Elsevier
Lactate dehydrogenase (LDH) is a key enzyme in the glycolysis, which has been reported
that the expression of LDH is elevated in a variety of cancer types and can promote tumor …

Recent advances on discovery of enzyme inhibitors from natural products using bioactivity screening

TC Yan, J Cao, LH Ye - Journal of Separation Science, 2022 - Wiley Online Library
The essence of enzymes is to keep the homeostasis and balance of humans by catalyzing
metabolic responses and modulating cells. Suppression of an enzyme slows the progress of …

Overview of in‐capillary enzymatic reactions using capillary electrophoresis

J Rozenski, AA Asfaw, A Van Schepdael - Electrophoresis, 2022 - Wiley Online Library
This review summarizes the research that has recently been performed on in‐capillary
enzymatic reactions integrated with capillary electrophoresis. The manuscript is subdivided …

Analytical settings for in-flow biocatalytic reaction monitoring

E Calleri, C Temporini, R Colombo, S Tengattini… - TrAC Trends in …, 2021 - Elsevier
The interest towards in-flow biocatalytic processes using immobilised enzyme reactors
(IMERs) has grown significantly over the past ten years. In an IMER, the enzyme is …

[HTML][HTML] Preparation of Alcohol Dehydrogenase–Zinc Phosphate Hybrid Nanoflowers through Biomimetic Mineralization and Its Application in the Inhibitor Screening

ML Luo, H Chen, GY Chen, S Wang, Y Wang, FQ Yang - Molecules, 2023 - mdpi.com
A biomimetic mineralization method was used in the facile and rapid preparation of
nanoflowers for immobilizing alcohol dehydrogenase (ADH). The method mainly uses ADH …

Screening of lipase inhibitors in citrus fruits by electrophoretically-mediated microanalysis combined with molecular docking

TC Yan, ZX Yue, YX Gu, H Zheng, J Cao - Journal of Food Composition …, 2022 - Elsevier
An efficient and environmentally friendly method for the online screening of lipase inhibitors
by capillary electrophoresis was established to investigate the inhibitory activity of citrus …

Microscale Quantification of the Inhibition of Neuraminidase Using Capillary Nanogel Electrophoresis

LD Casto-Boggess, LA Holland… - Analytical …, 2022 - ACS Publications
Neuraminidase inhibitors modulate infections that involve sialic acids, making quantitative
analyses of this inhibitory effect important for selecting and designing potential therapeutics …

Screening for pancreatic lipase natural modulators by capillary electrophoresis hyphenated to spectrophotometric and conductometric dual detection

GAHD Banni, R Nasreddine, S Fayad, P Cao-Ngoc… - Analyst, 2021 - pubs.rsc.org
The search for novel pancreatic lipase (PL) inhibitors has gained increasing attention in
recent years. For the first time, a dual detection capillary electrophoresis (CE)-based …