The ability of bacteria to develop resistance to antimicrobial agents poses problems in the
treatment of numerous bacterial infections. One method to circumvent permeability-mediated …

Iron overload cardiomyopathy (IOC) is a major cause of death in patients with diseases
associated with chronic anemia such as thalassemia or sickle cell disease after chronic …

Background—Chronic iron overload (CIO) is associated with blood disorders such as
thalassemias and hemochromatosis. A major prognostic indicator of survival in patients with …

Introduction: Deferasirox effectively controls liver iron concentration; however, little is known
regarding its ability to remove stored cardiac iron. Deferiprone seems to have increased …

Iron overload can lead to iron deposits in many tissues, particularly in the heart. It has also
been shown to be associated with elevated oxidative stress in tissues. Elevated cardiac iron …

Both iron overload and deficiency can promote development of cardiomyopathy. Advances
in our knowledge from recent research have indicated numerous potential cellular …

Introduction: Combined therapy with deferoxamine (DFO) and deferasirox (DFX) may be
performed empirically when DFX monotherapy fails. Given the lack of published data on this …

New developments in iron chelators : Current Opinion in Hematology New developments in
iron chelators : Current Opinion in Hematology Log in or Register Subscribe to journalSubscribe …

The present study aimed to investigate the impact of hydrogen (H2) on chronic intermittent
hypoxia (CIH)-induced cardiac hypertrophy in mice by modulating iron metabolism …

Introduction Sideroblastic cardiomyopathy secondary to repeated blood transfusions is a
feared complication in thalassaemia. Control of myocardial iron is thus becoming the …