In current drug delivery scenario, despite numerous scientific efforts, efficient ocular drug
delivery remains a challenge for pharmaceutical scientists. In ocular drug delivery system …

Nanosuspension: A novel approch to enhance solubility of poorly water soluble drugs - A review
Page 1 Review Article Nanosuspension: A novel approch to enhance solubility of poorly water …

Solubility is the crucial factor for drug effectiveness, independence of the route of
administration. Large proportions of newly discovered drugs are water insoluble, and …

The relative motion and collision between grinding media in a wet-stirred accelerator mill
are modelled using the discrete element method (DEM) coupled with computational fluid …

Poor water solubility and slow dissolution rate are issues for the majority of upcoming and
existing biologically active compounds. Simvastatin is poorly water-soluble drug and its …

Background: A nanosuspension is a colloidal dispersion of submicron drug particles. Most of
the new drugs are poorly soluble in both water and organic solvents. To overcome such …

Poor water solubility and slow dissolution rate are issues drug content and polydispersity
index. The obtained for the majority of upcoming and existing biologically results showed …

Main objectives to develop Aceclofenac Nanosuspension are to enhance solubility and
dissolution rate of poorly soluble Drug (Aceclofenac), substantially leading to its …

PURPOSE: PIK75 is a specific inhibitor of the p110 α isoform of phosphatidylinositol-3-
kinase, an enzyme which is upregulated in several human cancers. However its poor water …

Background: Nanosuspension has arisen as a lucrative, remunerative, as well as a potent
approach to improve the solubility and dissolution rate of poorly soluble drug entities …