Rat postimplantation whole-embryo culture (WEC) is a promising alternative test for the
assessment of developmental toxicity. Toxicogenomic-based approaches may improve the …

BACKGROUND: Toxicology studies utilizing animals and in vitro cellular or tissue
preparations have been used to study the toxic effects and mechanism of action of drugs …

Previous embryonic fish data have shown caffeine to induce potential teratogenic and long-
term neurodevelopmental outcomes through oxidative stress-mediated apoptosis. In this …

Epidemiological investigations have confirmed that prenatal caffeine intake could increase
the incidence rate of intrauterine growth retardation (IUGR) and multiple diseases after birth …

Our laboratory recently developed a mouse model of transplacental induction of lymphoma,
lung and liver cancer by the polycyclic aromatic hydrocarbon, dibenzo [a, l] pyrene (DBP) …

Ethanol (H3C-CH2OH, CAS no. 64-17-5) is an extensively used solvent, reactant and
intermediary product. In the industrial setting, ethanol is used as an antifreeze, as a fuel, as a …

Parkinson's disease (PD) is the second most common neurodegenerative disorder, affecting
1% of the world population age 65 and older. 1, 2 The number of individuals afflicted by PD …

Cigarette smoke (CS) exposure during pregnancy can lead to profound adverse effects on
fetal development. Although CS contains several thousand chemicals, nicotine has been …

Few signaling molecules have as much potential to influence the developing mammal as the
nucleoside adenosine. Adenosine levels increase rapidly with tissue hypoxia and …

This study was conducted to identify daily caffeine intakes in beverages for elementary
school children and to evaluate its effectiveness after nutrition education. The caffeine …