Cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options

J Jankowski, J Floege, D Fliser, M Böhm, N Marx - Circulation, 2021 - Am Heart Assoc
Patients with chronic kidney disease (CKD) exhibit an elevated cardiovascular risk
manifesting as coronary artery disease, heart failure, arrhythmias, and sudden cardiac …

The Hippo signalling pathway and its implications in human health and diseases

M Fu, Y Hu, T Lan, KL Guan, T Luo… - Signal transduction and …, 2022 - nature.com
As an evolutionarily conserved signalling network, the Hippo pathway plays a crucial role in
the regulation of numerous biological processes. Thus, substantial efforts have been made …

[HTML][HTML] Harmonizing acute and chronic kidney disease definition and classification: report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus …

NH Lameire, A Levin, JA Kellum, M Cheung… - Kidney international, 2021 - Elsevier
Kidney disease is an important public health problem. Both acute kidney injury (AKI) and
chronic kidney disease (CKD) have been well defined and classified leading to improved …

[HTML][HTML] Nomenclature for kidney function and disease: report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference

AS Levey, KU Eckardt, NM Dorman, SL Christiansen… - Kidney international, 2020 - Elsevier
The worldwide burden of kidney disease is rising, but public awareness remains limited,
underscoring the need for more effective communication by stakeholders in the kidney …

Kidney damage causally affects the brain cortical structure: a Mendelian randomization study

X Chen, J Kong, J Pan, K Huang, W Zhou, X Diao… - …, 2021 - thelancet.com
Background Alterations in the brain cortical structures of patients with chronic kidney
disease (CKD) have been reported; however, the cause has not been determined yet …

A catalog of genetic loci associated with kidney function from analyses of a million individuals

M Wuttke, Y Li, M Li, KB Sieber, MF Feitosa, M Gorski… - Nature …, 2019 - nature.com
Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic
complications. Through trans-ancestry meta-analysis of genome-wide association studies of …

NAFLD as a driver of chronic kidney disease

CD Byrne, G Targher - Journal of hepatology, 2020 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are worldwide
public health problems, affecting up to 25–30%(NAFLD), and up to 10–15%(CKD) of the …

Chronic kidney disease

P Romagnani, G Remuzzi, R Glassock… - Nature reviews Disease …, 2017 - nature.com
Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural
abnormalities or impaired excretory renal function suggestive of a loss of functional …

Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy

A Levin, M Tonelli, J Bonventre, J Coresh, JA Donner… - The Lancet, 2017 - thelancet.com
The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …

Workers' health and productivity under occupational heat strain: a systematic review and meta-analysis

AD Flouris, PC Dinas, LG Ioannou, L Nybo… - The Lancet Planetary …, 2018 - thelancet.com
Background Occupational heat strain (ie, the effect of environmental heat stress on the body)
directly threatens workers' ability to live healthy and productive lives. We estimated the …