Background GCA is a large vessel vasculitis affecting older people, with the highest
incidence among persons 70–79 years of age [1]. Due to forecasted demographic changes …

Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are closely related conditions
characterized by systemic inflammation, a predominant IL-6 signature, an excellent …

Background More than half of patients with polymyalgia rheumatica have a relapse during
tapering of glucocorticoid therapy. Previous studies have suggested that interleukin-6 …

Importance Few treatments are available for patients with glucocorticoid-dependent
polymyalgia rheumatica. IL-6 antagonists may reduce disease activity in patients with active …

Importance Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are related
inflammatory disorders occurring in persons aged 50 years and older. Diagnostic and …

GCA and PMR are conditions of older persons that frequently overlap. The traditional
concept of GCA has focused on cranial symptoms such as headache and visual …

There is convincing evidence for the known and unambiguously accepted beneficial effects
of glucocorticoids at low dosages. However, the implementation of existing …

Polymyalgia rheumatica is an inflammatory disease that affects the shoulder, the pelvic
girdles, and the neck, usually in individuals older than 50 years. Increases in acute phase …

Polymyalgia rheumatica (PMR) is the most common inflammatory rheumatic disease
affecting people older than 50 years and is 2–3 times more common in women. The most …

Objectives To develop treat-to-target (T2T) recommendations in giant cell arteritis (GCA) and
polymyalgia rheumatica (PMR). Methods A systematic literature review was conducted to …