This protocol explains how to perform a fast SCENIC analysis alongside standard best
practices steps on single-cell RNA-sequencing data using software containers and Nextflow …

Summary On April 21, 2015, the first SCN 8A Encephalopathy Research Group convened in
Washington, DC, to assess current research into clinical and pathogenic features of the …

A better understanding of human hepatocellular carcinoma (HCC) pathogenesis at the
molecular level will facilitate the discovery of tumor-initiating events. Transcriptome …

With the advent of ribosome profiling, a next generation sequencing technique providing a
“snap-shot''of translated mRNA in a cell, many short open reading frames (sORFs) with …

Although the Human Genome Project was completed 4 years ago, the catalog of human
protein-coding genes remains a matter of controversy. Current catalogs list a total of≈ …

Effective use of the human and mouse genomes requires reliable identification of genes and
their products. Although multiple public resources provide annotation, different methods are …

Objectives Recently, an increasing number of studies have revealed that N6-
methyladenosine (m6A) functions as a significant post-transcriptional modification which …

Recent studies strongly indicate that aberrations in the control of gene expression might
contribute to the initiation and progression of Alzheimer's disease (AD). In particular …

Genome browser provides a graphical interface for users to browse, search, retrieve and
analyze genomic sequence and annotation data. Web-based genome browsers can be …

A number of studies require the determination of the genetic sex of mouse embryos before
sexual differentiation and/or of mutant mice that display partial or complete sex reversal. The …