Although β2-adrenergic receptors (β2AR) are expressed on most cell types, mechanisms
that establish expression levels and regulate expression by chronic agonist remain unclear …

Ferns are important components of plant communities on earth, but their genomes are
generally very large, with many redundant genes, making whole genome sequencing of …

Background: Detection of SHOX2 methylation has been used to assist in the early diagnosis
of lung cancer in many hospitals as SHOX2 may be important in the tumorigenesis of lung …

Colorectal cancer (CRC) is one of the most common and lethal malignancies. The
identification of minimally invasive and precise biomarkers is an urgent need for the early …

Background Although ultra-high risk for schizophrenia (UHR) is related to both genetic and
environment factors, the precise pathogenesis is still unknow. To date, few studies have …

Objectives. Prolyl 4‐hydroxylase subunit alpha 1 (P4HA1) plays a crucial role in modulating
extracellular matrix component and promoting tumor progression by changing tumor …

Increasing evidence reveals sex as an important factor in the development of Parkinson's
disease (PD), but associations between genes on the sex chromosomes and PD remain …

Alternative splicing of pre-mRNAs is a central process to the generation of proteome
complexity. However, many alternative mRNA isoforms carry premature termination codons …

Self-cleaving ribozymes are catalytically active RNAs that cleave themselves into a 5′-
fragment with a 2′, 3′-cyclic phosphate and a 3′-fragment with a 5′-hydroxyl. They are …

The knowledge of the human genome is in continuous progression: a large number of
databases have been developed to make meaningful connections among worldwide …