Epitranscriptomic modifications in mesenchymal stem cell differentiation: advances, mechanistic insights, and beyond
J Zheng, Y Lu, Y Lin, S Si, B Guo, X Zhao… - Cell Death & …, 2024 - nature.com
RNA modifications, known as the “epitranscriptome”, represent a key layer of regulation that
influences a wide array of biological processes in mesenchymal stem cells (MSCs). These …
influences a wide array of biological processes in mesenchymal stem cells (MSCs). These …
[HTML][HTML] N6-methyladenosine in vascular aging and related diseases: clinical perspectives
C Li, L Liu, S Li, YS Liu - Aging and Disease, 2024 - ncbi.nlm.nih.gov
Aging leads to progressive deterioration of the structure and function of arteries, which
eventually contributes to the development of vascular aging-related diseases. N 6 …
eventually contributes to the development of vascular aging-related diseases. N 6 …
[HTML][HTML] METTL3-dependent N6-methyladenosine modification is involved in berberine-mediated neuroprotection in ischemic stroke by enhancing the stability of …
J Hu, H Duan, J Zou, W Ding, Z Wei, Q Peng… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Ischemic stroke (IS) is one of the principal causes of disability and death worldwide.
Berberine (BBR), derived from the traditional Chinese herbal medicine Huang Lian, has …
Berberine (BBR), derived from the traditional Chinese herbal medicine Huang Lian, has …
[HTML][HTML] Stem cell-derived extracellular vesicles in the therapeutic intervention of Alzheimer's Disease, Parkinson's Disease, and stroke
W Zhou, X Wang, Y Dong, P Gao, X Zhao, M Wang… - Theranostics, 2024 - ncbi.nlm.nih.gov
With the increase in the aging population, the occurrence of neurological disorders is rising.
Recently, stem cell therapy has garnered attention due to its convenient sourcing, minimal …
Recently, stem cell therapy has garnered attention due to its convenient sourcing, minimal …
Research progress and challenges of stem cell therapy for ischemic stroke
Z Cha, Y Qiao, Q Lu, Q Wang, X Lu… - Frontiers in Cell and …, 2024 - frontiersin.org
Ischemic stroke is a significant global cause of death and disability. Currently, treatment
options for acute ischemic stroke are limited to intravenous thrombolysis and mechanical …
options for acute ischemic stroke are limited to intravenous thrombolysis and mechanical …
Effects of Bone Marrow Mesenchymal Stem Cell-Derived Exosomes in Central Nervous System Diseases
M Chai, G Su, W Chen, J Gao, Q Wu, J Song… - Molecular …, 2024 - Springer
Central nervous system (CNS) diseases are one of the diseases that threaten human health.
The delivery of drugs targeting the CNS has always been a significant challenge; the blood …
The delivery of drugs targeting the CNS has always been a significant challenge; the blood …
Human Plasma‐Derived Extracellular Vesicles Protect Against Cerebral Ischemia‐Reperfusion Injury via HSP27 Phosphorylation
Y Wang, H Yang, L Zhao, X Yin, S Ai, M Hu… - Advanced …, 2024 - Wiley Online Library
Ischemic stroke (IS) has become a serious public health problem, with patients undergoing
endovascular treatment experiencing ischemia‐reperfusion (I/R) injury, which exacerbates …
endovascular treatment experiencing ischemia‐reperfusion (I/R) injury, which exacerbates …
Neuroprotective effects of exosomes derived from bone marrow mesenchymal stem cells treated by Musk Ketone on ischemic stroke
C Chen, D Feng, F Lu, J Qin, L Dun, Z Liao… - Journal of Stroke and …, 2024 - Elsevier
Objectives Ischemic stroke (IS) is a leading cause of morbidity and mortality globally. This
study aimed to investigate the role of exosomes (Exo) derived from bone marrow …
study aimed to investigate the role of exosomes (Exo) derived from bone marrow …
Recent Advances and Therapeutic Implications of 2-Oxoglutarate-Dependent Dioxygenases in Ischemic Stroke
J Xie, Z Zhang - Molecular Neurobiology, 2024 - Springer
Ischemic stroke is a common disease with a high disability rate and mortality, which brings
heavy pressure on families and medical insurance. Nowadays, the golden treatments for …
heavy pressure on families and medical insurance. Nowadays, the golden treatments for …
Exosomes: A Cellular Communication Medium That Has Multiple Effects On Brain Diseases
X Fang, D Zhou, X Wang, Y Ma, G Zhong, S Jing… - Molecular …, 2024 - Springer
Exosomes, as membranous vesicles generated by multiple cell types and secreted to
extracellular space, play a crucial role in a range of brain injury–related brain disorders by …
extracellular space, play a crucial role in a range of brain injury–related brain disorders by …