Hormonal regulation of the differentiation of cultured ovarian granulosa cells
1. Cell Culture Approach to the Study of Granulosa Cells In 1672, Regnier de Graaf first
described the differentiation of ovarian follicles into the corpus luteum. He stated that “age …
described the differentiation of ovarian follicles into the corpus luteum. He stated that “age …
Extrapituitary actions of gonadotropin-releasing hormone
AJW Hsueh, PBC Jones - Endocrine Reviews, 1981 - academic.oup.com
Harris (1) first proposed that the anterior pituitary gland is controlled by hypothalamic
releasing factors. After the subsequent purification and sequencing of gonadotropin …
releasing factors. After the subsequent purification and sequencing of gonadotropin …
Puberty in the rat
SR Ojeda, MK Skinner - Knobil and Neill's physiology of …, 2006 - ohsu.elsevierpure.com
This chapter discusses the modulatory influences regulating the timing of puberty in rats.
The developmental process that leads to puberty in the female rat is based on an …
The developmental process that leads to puberty in the female rat is based on an …
An increased intraovarian synthesis of nerve growth factor and its low affinity receptor is a principal component of steroid-induced polycystic ovary in the rat
A form of polycystic ovary (PCO) resembling some aspects of the human PCO syndrome can
be induced in rats by a single injection of estradiol valerate (EV). An increase in sympathetic …
be induced in rats by a single injection of estradiol valerate (EV). An increase in sympathetic …
Protein kinase B is obligatory for follicle-stimulating hormone-induced granulosa cell differentiation
AJ Zeleznik, D Saxena, L Little-Ihrig - Endocrinology, 2003 - academic.oup.com
Although FSH receptors are linked to the cAMP second messenger system, additional
intracellular signaling pathways appear to be required for the induction of aromatase and …
intracellular signaling pathways appear to be required for the induction of aromatase and …
A role for neurotransmitters in early follicular development: induction of functional follicle-stimulating hormone receptors in newly formed follicles of the rat ovary
A Mayerhofer, GA Dissen, ME Costa, SR Ojeda - Endocrinology, 1997 - academic.oup.com
The initiation of follicular growth in the mammalian ovary is a gonadotropin-independent
phenomenon. Although some of the intraovarian signaling molecules that control the later …
phenomenon. Although some of the intraovarian signaling molecules that control the later …
Involvement of nerve growth factor in female sexual development
The ovary is innervated by noradrenergic and peptidergic fibers. Treatment of neonatal rats
with antibodies to nerve growth factor (NGF Ab) resulted in failure of the sympathetic …
with antibodies to nerve growth factor (NGF Ab) resulted in failure of the sympathetic …
Hormonal regulation of granulosa cell inhibin biosynthesis
TA BICSAK, EM TUCKER, S CAPPEL… - …, 1986 - academic.oup.com
The hormonal regulation of inhibin production by cultured granulosa cells from immature
hypophysectomized, estrogen-treated rats was examined using a specific RIA which detects …
hypophysectomized, estrogen-treated rats was examined using a specific RIA which detects …
Prepubertal ovarian function is finely regulated by direct adrenergic influences. Role of noradrenergic innervation
LI Aguado, SR Ojeda - Endocrinology, 1984 - academic.oup.com
In the rat, the main source of adrenergic fibers innervating nonvascular ovarian tissue is the
superior ovarian nerve (SON). To determine the influence of the SON on prepubertal ovarian …
superior ovarian nerve (SON). To determine the influence of the SON on prepubertal ovarian …
Somatomedin-C enhances induction of luteinizing hormone receptors by follicle-stimulating hormone in cultured rat granulosa cells
ELIY ADASHI, CE ESNICK, ME SVOBODA… - …, 1985 - academic.oup.com
Recent studies have documented the ability of somatomedin-C (Sm-C) to synergize with
FSH in the induction of rat granulosa cell progesterone biosynthesis. This direct …
FSH in the induction of rat granulosa cell progesterone biosynthesis. This direct …