Introduction: The past decade has seen the development and widespread use of tyrosine
kinase inhibitors (TKIs) targeting a mutated EGFR (mEGFR) for the treatment of metastatic …

Purpose To map functional bone marrow (BM) by 2-deoxy-2-[18 F] fluoro-d-glucose ([18 F]
FDG) positron emission tomography (PET) in the vertebral column of lung cancer patients …

Epidermal growth factor receptor (EGFR) is a member of the receptor tyrosine kinase family
and plays key roles in the regulation of fundamental cellular processes, including cell …

Simotinib is a novel oral small-molecule tyrosine kinase inhibitor that has demonstrated
equal or superior antineoplastic activities to erlotinib in preclinical studies. In support of a …

Cancer is one of the dominant causes of death worldwide while lifelong prognosis is still
inauspicious. The maturation of the cancer is seen as a process of transformation of a …

Introduction: Increased understanding in intracellular signaling pathways leading to
carcinogenesis, proliferation, migration, invasion, angiogenesis, and anti-apoptosis of …

Characterized tissue with pathological grading and blood samples as well as other biofluids
forms the basis for all biobanks as a resource in modern life science. Biobanks are accessed …

Non-small cell lung cancer (NSCLC) accounts for approximately 80-85% of all cases of lung
cancer, and it is the most common cause of death in men and second only to breast cancer …

Background Correct diagnosis and staging are required for optimal treatment choice in lung
cancer patients. This retrospective, patient medical records study investigated the clinical …

Los medicamentos de origen biotecnol—gico pueden ser anticuerpos monoclonales o
molŽculas peque–as dise–adas para actuar sobre blancos terapŽuticos definidos. Se hizo …