[HTML][HTML] Beyond solid-state lighting: Miniaturization, hybrid integration, and applications of GaN nano-and micro-LEDs

HS Wasisto, JD Prades, J Gülink, A Waag - Applied Physics Reviews, 2019 - pubs.aip.org
Gallium nitride (GaN) light-emitting-diode (LED) technology has been the revolution in
modern lighting. In the last decade, a huge global market of efficient, long-lasting, and …

Cochlear implant

JG Naples, MJ Ruckenstein - Otolaryngologic Clinics of North …, 2020 - oto.theclinics.com
It is impossible to overstate the medical and societal impact of cochlear implant (CI). The
introduction of this device allowed otolaryngologists to restore auditory input in deafened …

Structural insights into ion conduction by channelrhodopsin 2

O Volkov, K Kovalev, V Polovinkin, V Borshchevskiy… - Science, 2017 - science.org
INTRODUCTION Ion channels are integral membrane proteins that upon stimulation
modulate the flow of ions across the cell or organelle membrane. The resulting electrical …

On the horizon: cochlear implant technology

JP Roche, MR Hansen - Otolaryngologic Clinics of North America, 2015 - oto.theclinics.com
Most patients with hearing loss significant enough to result in social dysfunction can be
treated with nonsurgical interventions. In many instances, environmental manipulations are …

A wireless, solar-powered, optoelectronic system for spatial restriction-free long-term optogenetic neuromodulations

J Park, K Kim, Y Kim, TS Kim, IS Min, B Li, YU Cho… - Science …, 2023 - science.org
Numerous wireless optogenetic systems have been reported for practical tether-free
optogenetics in freely moving animals. However, most devices rely on battery-powered or …

Towards the optical cochlear implant: optogenetic approaches for hearing restoration

A Dieter, D Keppeler, T Moser - EMBO molecular medicine, 2020 - embopress.org
Cochlear implants (CI s) are considered the most successful neuroprosthesis as they enable
speech comprehension in the majority of half a million CI users suffering from sensorineural …

Depth-specific optogenetic control in vivo with a scalable, high-density μLED neural probe

R Scharf, T Tsunematsu, N McAlinden, MD Dawson… - Scientific reports, 2016 - nature.com
Controlling neural circuits is a powerful approach to uncover a causal link between neural
activity and behaviour. Optogenetics has been widely adopted by the neuroscience …

High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics

T Mager, D Lopez de la Morena, V Senn… - Nature …, 2018 - nature.com
Optogenetics revolutionizes basic research in neuroscience and cell biology and bears
potential for medical applications. We develop mutants leading to a unifying concept for the …

Near physiological spectral selectivity of cochlear optogenetics

A Dieter, CJ Duque-Afonso, V Rankovic… - Nature …, 2019 - nature.com
Cochlear implants (CIs) electrically stimulate spiral ganglion neurons (SGNs) and partially
restore hearing to half a million CI users. However, wide current spread from intracochlear …

Design and manufacturing challenges of optogenetic neural interfaces: a review

SB Goncalves, JF Ribeiro, AF Silva… - Journal of neural …, 2017 - iopscience.iop.org
Optogenetics is a relatively new technology to achieve cell-type specific neuromodulation
with millisecond-scale temporal precision. Optogenetic tools are being developed to …