This report on vitamin B-12 (B12) is part of the Biomarkers of Nutrition for Development
(BOND) Project, which provides state-of-the art information and advice on the selection, use …

Vitamin B12 (cobalamin) is an essential cofactor for two metabolic pathways. It is obtained
principally from food of animal origin. Cobalamin becomes bioavailable through a series of …

Summary of key recommendations The clinical picture is the most important factor in
assessing the significance of test results assessing cobalamin status because there is no …

Vitamin B12 is an essential cofactor that is integral to methylation processes important in
reactions related to DNA and cell metabolism, thus a deficiency may lead to disruption of …

The detection and correction of vitamin B 12 (B 12) deficiency prevents megaloblastic
anaemia and potentially irreversible neuropathy and neuropsychiatric changes. B 12 status …

There is a strong biological premise for including vitamin B12 with folic acid in strategies to
prevent neural tube defects (NTDs), due to the closely interlinked metabolism of these two …

Studies on the nutritional status of vegetarians in Spain are lacking. Prevention of vitamin
B12 deficiency is the main concern, as dietary sources are of animal origin. The present …

Methylmalonic acid (MMA) is a by-product of propionic acid metabolism through the vitamin
B 12 (cobalamin)-dependent enzyme methylmalonyl CoA mutase. Elevated MMA …

Background: Athletes and coaches believe in the ergogenic effect of vitamin B12 (which
results from enhanced erythropoiesis) and they often insist on its unjustified …

Background Crohn's disease (CD) is a risk factor for vitamin B12 deficiency due to frequent
involvement of the terminal ileum. Conventional screening for B12 deficiency with serum …