▪ Abstract Comparative modeling predicts the three-dimensional structure of a given protein
sequence (target) based primarily on its alignment to one or more proteins of known …

Comparative protein structure modeling predicts the three‐dimensional structure of a given
protein sequence (target) based primarily on its alignment to one or more proteins of known …

Clustering has a wide range of applications in life sciences and over the years has been
used in many areas ranging from the analysis of clinical information, phylogeny, genomics …

Multiple structural alignment is a fundamental problem in structural genomics. In this article,
we define a reliable and robust algorithm, MUSTANG (MUltiple STructural AligNment …

Abstract VIPERdb (http://viperdb. scripps. edu) is a relational database and a web portal for
icosahedral virus capsid structures. Our aim is to provide a comprehensive resource specific …

Here, we present MultiProt, a fully automated highly efficient technique to detect multiple
structural alignments of protein structures. MultiProt finds the common geometrical cores …

We used sequence and structural comparisons to determine the fold for eukaryotic ornithine
decarboxylase, which we found is related to alanine racemase. These enzymes have no …

For single-domain proteins, we examine the completeness of the structures in the current
Protein Data Bank (PDB) library for use in full-length model construction of unknown …

Publisher Summary This chapter discusses the methods that are flexible enough to align
distantly related structures and, therefore, most suitable for identifying and analyzing protein …

Most bioinformatics analyses require the assembly of a multiple sequence alignment. It has
long been suspected that structural information can help to improve the quality of these …