Molecular modeling methods are being used routinely for the prediction and analysis of
three-dimensional structures of biological macromolecules. Generally, prediction of three …

The 22 kDa haem-binding protein, p22HBP, is highly expressed in erythropoietic tissues
and binds to a range of metallo-and non-metalloporphyrin molecules with similar affinities …

Abstract Many (α/β) 8‐barrel enzymes contain their conserved sequence regions at or
around the β‐strand segments that are often preceded and succeeded by glycines and …

A method of multiple sequence alignment is described based on the double dynamic
programming (DDP) algorithm previously used for treating structural constraints …

Introduction to Computational Proteomics introduces the field of computational biology
through a focused approach that tackles the different steps and problems involved with …

Primary amino acid content and the geometry of the folded protein 3D structure are major
parameters of protein function. During the course of evolution the protein 3D structure is …

Local structural alignment is an effective method to detect the local similarities between two
protein structures. Orengo & Taylor (1993) have already developed a local structural …

The availability of the complete genomic sequences of many species, including human, has
raised enormous expectations in medicine, pharmacology, ecology, biotechnology and …

«L'esprit scientifique nous interdit d'avoir une opinion sur des questions que nous ne
comprenons pas, sur des questions que nous ne savons pas formuler clairement. Avant tout …