Toxicity profile of epidermal growth factor receptor tyrosine kinase inhibitors for patients with lung cancer: A systematic review and network meta-analysis

Y Zhao, B Cheng, Z Chen, J Li, H Liang, Y Chen… - Critical Reviews in …, 2021 - Elsevier
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are treatments
commonly used for lung cancer. The toxicity profile including toxicity incidence, severity, and …

[HTML][HTML] 中国晚期原发性肺癌诊治专家共识( 2016 年版)

石远凯, 孙燕, 于金明, 丁翠敏, 王子平… - Chinese Journal of …, 2016 - ncbi.nlm.nih.gov
作者单位: 100021 北京, 中国医学科学院北京协和医学院肿瘤医院, 抗肿瘤分子靶向药物临床
研究北京市重点实验室(石远凯, 孙燕, 韩晓红, 郏博, 韩颖, 黄昱); 250117 济南 …

Gefitinib for advanced non‐small cell lung cancer

EHA Sim, IA Yang, R Wood‐Baker… - Cochrane Database …, 2018 - cochranelibrary.com
Background The role of gefitinib for the treatment of advanced non‐small cell lung cancer
(NSCLC) is evolving. We undertook a systematic review to evaluate the available evidence …

Pneumonitis in advanced non-small-cell lung cancer patients treated with EGFR tyrosine kinase inhibitor: meta-analysis of 153 cohorts with 15,713 patients: meta …

CH Suh, HS Park, KW Kim, J Pyo, H Hatabu, M Nishino - Lung cancer, 2018 - Elsevier
Purpose Pneumonitis is a significant toxicity of EGFR tyrosine kinase inhibitors (EGFR-TKI)
in non-small-cell lung cancer (NSCLC) patients. We studied the incidence of pneumonitis in …

Phase II study of biomarker-guided neoadjuvant treatment strategy for IIIA-N2 non-small cell lung cancer based on epidermal growth factor receptor mutation status

W Zhong, X Yang, H Yan, X Zhang, J Su… - Journal of Hematology & …, 2015 - Springer
Background Neoadjuvant erlotinib and customized adjuvant therapy are appealing but
controversial. The purpose of this study was to evaluate the role of biomarker-guided …

EZH2 inhibitors reverse resistance to gefitinib in primary EGFR wild-type lung cancer cells

H Gong, Y Li, Y Yuan, W Li, H Zhang, Z Zhang, R Shi… - BMC cancer, 2020 - Springer
Background Lung cancer is the leading cause of cancer-related deaths worldwide. Non-
small cell lung cancer (NSCLC) is the most common type of lung cancer. In traditional anti …

The changing landscape of clinical trial and approval processes in China

Q Zhou, XY Chen, ZM Yang, YL Wu - Nature Reviews Clinical …, 2017 - nature.com
In the past decade, the standards of clinical trials in China have moved closer to
international standards, thus encouraging the development of innovative drugs. However, a …

A review of recent advances in the treatment of elderly and poor performance NSCLC

JA Carmichael, D Wing-san Mak, M O'Brien - Cancers, 2018 - mdpi.com
Until recently, chemotherapy has remained the mainstay of treatment for the majority of
patients with advanced non-small cell lung cancer (NSCLC). Excellent responses have …

Evolving landscape of tumor molecular profiling for personalized cancer therapy: a comprehensive review

NLX Syn, WP Yong, BC Goh, SC Lee - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Tumour molecular profiling has been at the crossroads of large-scale
integrative genomic studies and major clinical trials over the past 5 years and has provided …

Pemetrexed for advanced stage nonsquamous non-small cell lung cancer: latest evidence about its extended use and outcomes

P Tomasini, F Barlesi, C Mascaux… - … Advances in Medical …, 2016 - journals.sagepub.com
Non-small cell lung cancer (NSCLC) is still the leading cause of cancer-related death, and
the treatment of advanced NSCLC relies on systemic treatments. During the last decade …