Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease that inevitably
progress to end-stage kidney disease. Intervention strategies such as blood glucose control …

Introduction: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease
(CKD) and end-stage renal disease (ESRD). Beyond the new anti-diabetic drugs that …

Vitamin B6 is a cofactor for approximately 150 reactions that regulate the metabolism of
glucose, lipids, amino acids, DNA, and neurotransmitters. In addition, it plays the role of …

Liver fibrosis is a common chronic hepatic disease. This study was done to examine the
effect of pyridoxamine against thioacetamide-induced hepatic fibrosis. Animals were divided …

This research aimed to explore the protective effect of quercetin against nephrotoxicity
induced by four organophosphate pesticide mixtures (PM) using untargeted metabolomics …

Objective We investigated the protective effects of pyridoxamine against metabolic and
microcirculatory complications in nonalcoholic fatty liver disease. Methods Nonalcoholic fatty …

The multi-ligand receptor for advanced glycation end-products (RAGE) and its ligands are
contributing factors in autoimmunity, cancers, and infectious disease. RAGE activation is …

Introduction This study aimed to investigate changes in renal function and the AGE-RAGE
axis in the kidney of a non-genetic animal model of metabolic syndrome (MetS) induced by …

Background and aims Vitamin B6 is involved in a large spectrum of physiological processes
and comprises of the vitamers pyridoxamine (PM), pyridoxal (PL), pyridoxine (PN), and their …

Diabetes mellitus, a complex metabolic disorder, presents a growing global health
challenge. In 2021, there were 529 million diabetics worldwide. At the super-regional level …