Beneath the skin: a review of current trends and future prospects of transdermal drug delivery systems

AZ Alkilani, J Nasereddin, R Hamed, S Nimrawi… - Pharmaceutics, 2022 - mdpi.com
The ideal drug delivery system has a bioavailability comparable to parenteral dosage forms
but is as convenient and easy to use for the patient as oral solid dosage forms. In recent …

EGF, a veteran of wound healing: highlights on its mode of action, clinical applications with focus on wound treatment, and recent drug delivery strategies

K Shakhakarmi, JE Seo, S Lamichhane… - Archives of Pharmacal …, 2023 - Springer
Epidermal growth factor (EGF) has been used in wound management and regenerative
medicine since the late 1980s. It has been widely utilized for a long time and still is because …

Quality by design-driven zeta potential optimisation study of liposomes with charge imparting membrane additives

Z Németh, I Csóka, R Semnani Jazani, B Sipos… - Pharmaceutics, 2022 - mdpi.com
Liposomal formulations, as versatile nanocarrier systems suitable for targeted delivery, have
a highly focused role in the therapy development of unmet clinical needs and diagnostic …

Flexible nano-liposomes-based transdermal hydrogel for targeted delivery of dexamethasone for rheumatoid arthritis therapy

YP Zhao, JF Han, FY Zhang, TT Liao, R Na… - Drug Delivery, 2022 - Taylor & Francis
Rheumatoid arthritis (RA) is an inflammatory immune-mediated disease that can lead to
synovitis, cartilage destruction, and even joint damage. Dexamethasone (DEX) is a …

Liposomes under shear: structure, dynamics, and drug delivery applications

S Karaz, E Senses - Advanced NanoBiomed Research, 2023 - Wiley Online Library
The targeted delivery to specific locations while not causing damage to healthy tissues
efficiently remains a challenge in drug delivery systems. Through addressing this issue …

A comprehensive review on transethosomes as a novel vesicular approach for drug delivery through transdermal route

M Munir, M Zaman, MA Waqar… - Journal of Liposome …, 2024 - Taylor & Francis
Drug delivery through transdermal route is one of the effective methods for the application of
drugs. It overcomes many drawbacks which are encountered with the oral route. Moreover …

Ultrasound triggering of liposomal nanodrugs for cancer therapy: a review

WN Bahutair, WH Abuwatfa, GA Husseini - Nanomaterials, 2022 - mdpi.com
Efficient conventional chemotherapy is limited by its nonspecific nature, which causes
severe systemic toxicity that can lead to patient discomfort and low therapeutic efficacy. The …

Extracellular vesicles in vascular remodeling

C Ye, F Zheng, N Wu, G Zhu, X Li - Acta Pharmacologica Sinica, 2022 - nature.com
Vascular remodeling contributes to the development of a variety of vascular diseases
including hypertension and atherosclerosis. Phenotypic transformation of vascular cells …

Transfersome, an ultra-deformable lipid-based drug nanocarrier: an updated review with therapeutic applications

Simrah, A Hafeez, SA Usmani, MP Izhar - … -Schmiedeberg's Archives of …, 2024 - Springer
The application of nanotechnology with integration of chemical sciences is increasing
continuously in the management of diseases. The drug's physicochemical and …

Liposomes-based drug delivery systems of anti-biofilm agents to combat bacterial biofilm formation

Z Makhlouf, AA Ali, MH Al-Sayah - Antibiotics, 2023 - mdpi.com
All currently approved antibiotics are being met by some degree of resistance by the
bacteria they target. Biofilm formation is one of the crucial enablers of bacterial resistance …