Chagas disease in the United States: a public health approach

C Bern, LA Messenger, JD Whitman… - Clinical microbiology …, 2019 - Am Soc Microbiol
Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …

Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease

LA Messenger, MA Miles, C Bern - Expert review of anti-infective …, 2015 - Taylor & Francis
Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …

Genetic diversity of Trypanosoma cruzi in bats, and multilocus phylogenetic and phylogeographical analyses supporting Tcbat as an independent DTU (discrete …

L Lima, O Espinosa-Álvarez, PA Ortiz, JA Trejo-Varón… - Acta tropica, 2015 - Elsevier
Trypanosoma cruzi is a complex of phenotypically and genetically diverse isolates
distributed in six discrete typing units (DTUs) designated as TcI–TcVI. Five years ago, T …

Landscape ecology of Trypanosoma cruzi in the southern Yucatan Peninsula

SA López-Cancino, E Tun-Ku, HK De la Cruz-Felix… - Acta tropica, 2015 - Elsevier
Landscape interactions of Trypanosoma cruzi (Tc) with Triatoma dimidiata (Td) depend on
the presence and relative abundance of mammal hosts. This study analyzed a landscape …

The compatibility between Biomphalaria glabrata snails and Schistosoma mansoni: an increasingly complex puzzle

G Mitta, B Gourbal, C Grunau, M Knight… - Advances in …, 2017 - Elsevier
This review reexamines the results obtained in recent decades regarding the compatibility
polymorphism between the snail, Biomphalaria glabrata, and the pathogen, Schistosoma …

[HTML][HTML] Evidence and importance of genetic exchange among field populations of Trypanosoma cruzi

LA Messenger, MA Miles - Acta Tropica, 2015 - Elsevier
Many eukaryotic pathogenic microorganisms that were previously assumed to propagate
clonally have retained cryptic sexual cycles. The principal reproductive mode of …

Whole genome sequencing of Trypanosoma cruzi field isolates reveals extensive genomic variability and complex aneuploidy patterns within TcII DTU

JL Reis-Cunha, RP Baptista, GF Rodrigues-Luiz… - BMC genomics, 2018 - Springer
Background Trypanosoma cruzi, the etiologic agent of Chagas disease, is currently divided
into six discrete typing units (DTUs), named TcI-TcVI. TcII is among the major DTUs enrolled …

New insights into the evolution of the Trypanosoma cruzi clade provided by a new trypanosome species tightly linked to Neotropical Pteronotus bats and related to …

L Lima, O Espinosa-Álvarez, CM Pinto… - Parasites & vectors, 2015 - Springer
Background Bat trypanosomes are implicated in the evolution of the T. cruzi clade, which
harbours most African, European and American trypanosomes from bats and other …

Geographical, landscape and host associations of Trypanosoma cruzi DTUs and lineages

A Izeta-Alberdi, CN Ibarra-Cerdeña, DA Moo-Llanes… - Parasites & …, 2016 - Springer
Background The evolutionary history and ecological associations of Trypanosoma cruzi, the
need to identify genetic markers that can distinguish parasite subpopulations, and …

Detection of Trypanosoma cruzi in the saliva of diverse neotropical bats

LM Bergner, DJ Becker, C Tello… - Zoonoses and Public …, 2021 - Wiley Online Library
Trypanosoma cruzi is widely reported in bats, yet transmission routes remain unclear. We
present evidence from metagenomic sequence data that T. cruzi occurs in the saliva of …