Mass spectrometric analysis of urinary n-glycosylation changes in patients with Parkinson's disease

M Xu, H Jin, W Ge, L Zhao, Z Liu, Z Guo… - ACS Chemical …, 2023 - ACS Publications
Urine is thought to provide earlier and more sensitive molecular changes for biomarker
discovery than blood. Numerous glycoproteins, peptides, and free glycans are present in …

Fluorophore-glucan conjugate for oligosaccharide sensing in aqueous media

H Kurohara, Y Hori, M Numata, G Fukuhara - Polymer Journal, 2024 - nature.com
The ability to sense saccharides in aqueous media using conventional supramolecular
approaches was a turning point in modern chemistry. Herein, we performed oligosaccharide …

Tissue-specific O-GlcNAcylation profiling identifies substrates in translational machinery in Drosophila mushroom body contributing to olfactory learning

H Yu, D Liu, Y Zhang, R Tang, X Fan, S Mao, L Lv… - Elife, 2024 - elifesciences.org
O-GlcNAcylation is a dynamic post-translational modification that diversifies the proteome.
Its dysregulation is associated with neurological disorders that impair cognitive function, and …

Oligosaccharide sensing using fluorophore-probed curdlans in aqueous media

H Kurohara, Y Hori, M Numata… - ACS Applied Polymer …, 2023 - ACS Publications
Saccharide sensing in aqueous media has recently garnered considerable attention in
supramolecular and analytical chemistry; however, it still faces significant challenges …

Fluorophore-Probed Curdlan Polysaccharide Chemosensor:“Turn-On” Oligosaccharide Sensing in Aqueous Media

M Norikuni, Y Hori, M Numata, M Matsusaki, T Kida… - ACS …, 2024 - ACS Publications
The ability to sense saccharides in aqueous media has attracted much attention in
multidisciplinary sciences because the detection of ultrahigh concentrations of sugar chains …

Expanding Glycomic Investigations through Thiol-Derivatized Glycans

RD Hurst, A Nieves, M Brichacek - Molecules, 2023 - mdpi.com
N-(2-thioethyl)-2-aminobenzamide (TEAB), a novel glycan auxiliary, was synthesized and its
utility was evaluated. The auxiliary was conjugated to glycans by reductive amination with …

Diagonal Chromatography for the Isolation of O-Linked β-N-acetyl-D-Glucosaminylated (O-GlcNAcylated) Peptides in HeLa Cell Extracts

P Thawornpan, C Weeraphan… - Analytical …, 2024 - Taylor & Francis
Protein O-linked-N-acetylglucosaminylation (O-GlcNAcylation) is a dynamic post-
translational modification process that plays an essential role in biological activities …

Olfactory learning in Drosophila requires O-GlcNAcylation of mushroom body ribosomal subunits

H Yu, D Liu, Y Zhang, R Tang, X Fan, S Mao, L Lv… - bioRxiv, 2023 - biorxiv.org
O-GlcNAcylation is a dynamic post-translational modification that diversifies the proteome.
Its dysregulation is associated with neurological disorders that impair cognitive function, and …

Enrichment of glycoRNAs using galactose oxidase, hydrazide chemistry, and glycosidase digestion

X Miao, J Deng, X Wang, SY Wen, Z Zhou, S Li, X Yang… - bioRxiv, 2024 - biorxiv.org
Ribonucleic acid (RNA), essential for protein production and immune function, undergoes
glycosylation, a process that attaches carbohydrates to RNA, creating unique glycoRNAs …