The crosstalk between Nrf2 and NF-κB pathways in coronary artery disease: Can it be regulated by SIRT6?
E Casper - Life sciences, 2023 - Elsevier
Coronary artery disease (CAD) is the leading cause of death worldwide. Oxidative stress
and inflammation are major mechanisms responsible for the progression of CAD. Nuclear …
and inflammation are major mechanisms responsible for the progression of CAD. Nuclear …
Inflammatory mechanisms of diabetes and its vascular complications
LV Nedosugova, YV Markina, LA Bochkareva… - Biomedicines, 2022 - mdpi.com
The main cause of death in patients with type 2 DM is cardiovascular complications resulting
from the progression of atherosclerosis. The pathophysiology of the association between …
from the progression of atherosclerosis. The pathophysiology of the association between …
Diabetes mellitus promotes the development of atherosclerosis: the role of NLRP3
J Ye, L Li, M Wang, Q Ma, Y Tian, Q Zhang… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis is one of the main complications of diabetes mellitus, involving a variety of
pathogenic factors. Endothelial dysfunction, inflammation, and oxidative stress are hallmarks …
pathogenic factors. Endothelial dysfunction, inflammation, and oxidative stress are hallmarks …
Portrayal of NLRP3 inflammasome in atherosclerosis: current knowledge and therapeutic targets
We are witnessing the globalization of a specific type of arteriosclerosis with rising
prevalence, incidence and an overall cardiovascular disease burden. Currently …
prevalence, incidence and an overall cardiovascular disease burden. Currently …
Lowering n-6/n-3 Ratio as an Important Dietary Intervention to Prevent LPS-Inducible Dyslipidemia and Hepatic Abnormalities in ob/ob Mice
S Park, JJ Lee, J Lee, JK Lee, J Byun, I Kim… - International Journal of …, 2022 - mdpi.com
Obesity is closely associated with low-grade chronic and systemic inflammation and
dyslipidemia, and the consumption of omega-3 polyunsaturated fatty acids (n-3 PUFAs) may …
dyslipidemia, and the consumption of omega-3 polyunsaturated fatty acids (n-3 PUFAs) may …
Stem cell-based therapy: a promising treatment for diabetic foot ulcer
R El Hage, U Knippschild, T Arnold, I Hinterseher - Biomedicines, 2022 - mdpi.com
Diabetic foot ulcer (DFU) is a severe complication of diabetes and a challenging medical
condition. Conventional treatments for DFU have not been effective enough to reduce the …
condition. Conventional treatments for DFU have not been effective enough to reduce the …
Okra ameliorates hyperglycaemia in pre-diabetic and type 2 diabetic patients: A systematic review and meta-analysis of the clinical evidence
Background: Despite the use of available pharmaceutical drugs, high rates of metabolic
diseases and cardiovascular disorders are alarming. This calls for alternative therapies that …
diseases and cardiovascular disorders are alarming. This calls for alternative therapies that …
The role of the gut microbiome and trimethylamine oxide in atherosclerosis and age-related disease
R El Hage, N Al-Arawe, I Hinterseher - International Journal of Molecular …, 2023 - mdpi.com
The gut microbiome plays a major role in human health, and gut microbial imbalance or
dysbiosis is associated with disease development. Modulation in the gut microbiome can be …
dysbiosis is associated with disease development. Modulation in the gut microbiome can be …
ROS signaling in innate immunity via oxidative protein modifications
RR Manoharan, A Prasad, P Pospíšil… - Frontiers in …, 2024 - frontiersin.org
The innate immune response represents the first-line of defense against invading
pathogens. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been …
pathogens. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been …
Diabetic neuropathy of the retina and inflammation: perspectives
A clear connection exists between diabetes and atherosclerotic cardiovascular disease.
Consequently, therapeutic approaches that target both diseases are needed. Clinical trials …
Consequently, therapeutic approaches that target both diseases are needed. Clinical trials …