An impressive variety of new methodologies for the preparation of 18 F-labelled tracers and
ligands has appeared over the last decade. Most strategies of the newly developed …

The emerging technology of digital microfluidics is opening up the possibility of performing
radiochemistry at the microliter scale to produce tracers for positron emission tomography …

Despite the increasing importance of positron emission tomography (PET) imaging in
research and clinical management of disease, access to myriad new radioactive tracers is …

Positron emission tomography (PET) is a powerful diagnostic tool that holds incredible
potential for clinicians to track a wide variety of biological processes using specialized …

New platforms are enabling radiochemistry to be carried out in tiny, microliter-scale volumes,
and this capability has enormous benefits for the production of radiopharmaceuticals. These …

In this work, we introduce a low-cost open-source flow system that includes a dual syringe
pump with implemented pressure sensor and back pressure regulator. The entire system …

High specific activity is often a significant requirement for radiopharmaceuticals. To achieve
that with fluorine‐18 (18F)‐labeled probes, it is mandatory to start from no‐carrier–added …

A variety of crown ether metal complex fluorides (CEMCFs), such as [18-C-6K][F],[18-C-
6Cs][F],[18-C-6Rb][F], and [18-C-6Na][F]([18-C-6K]= 18-crown-6 potassium cation …

Positron emission tomography (PET) provides quantitative 3D visualization of physiological
parameters (eg, metabolic rate, receptor density, gene expression, blood flow) in real time in …

Before formulating radiopharmaceuticals for injection, it is necessary to remove various
impurities via purification. Conventional synthesis methods involve relatively large quantities …