Urothelial carcinoma (UC) is a frequent cause of cancer-related deaths worldwide.
Metastatic UC has been historically associated with poor prognosis, with a median overall …

Non-clear cell renal cell carcinomas are a miscellaneous group of tumors that include
different histological subtypes, each one characterized by peculiarity in terms of genetic …

Biliary tract cancer (BTC) patients usually have poor prognosis. Whereas combination
chemotherapy has been shown to improve survival in the frontline setting, second-line …

Genitourinary cancers (GCs) include a large group of different types of tumors localizing to
the kidney, bladder, prostate, testis, and penis. Despite highly divergent molecular patterns …

Introduction The aim of this paper was to perform a narrative review of the literature on the
available approaches in the treatment of two emerging subpopulations of metastatic renal …

Brain metastases (BMs) represent a negative prognostic factor for patients with solid
malignancies. BMs are generally approached with loco-regional treatments and the blood …

In the last few years, kidney cancer has undergone one of the most revolutionary progresses
in terms of ever-growing treatment options. The clear cell renal cell carcinoma (ccRCC) …

The last three decades have witnessed a revolution in the therapeutic scenario of metastatic
renal cell carcinoma (mRCC), due to the advent of novel agents including tyrosine kinase …

Renal cell carcinoma (RCC) is a frequent urological malignancy characterized by a high rate
of metastasis and lethality. The treatment strategy for advanced RCC has moved through …

Introduction: In the evolving treatment scenario of metastatic renal cell carcinoma,
cabozantinib is gaining increasing attention, presenting as a cornerstone therapy, both as a …