Polyphenols are secondary plant metabolites which have been shown to exert antioxidative
and antiinflamma tory effects in cell culture, rodent and human studies. Based on the fact …

Recent progress on the application of cytochrome P450 (P450) to bioconversion processes,
biosensors, and bioremediation were reviewed. Because regio-and enantioselective …

Abstract The European Commission asked EFSA for a scientific opinion on the risks for
animal and human health related to the presence of dioxins (PCDD/Fs) and DL‐PCBs in …

We determined the contamination status and accumulation profiles of polychlorinated
biphenyls (PCBs), hydroxylated PCB congeners (OH-PCBs), polybrominated diphenyl …

Biomonitoring studies show that humans carry a body burden of multiple classes of
contaminants which are not often studied together. Many of these chemicals may be …

Cytochromes P450 are a class of metalloproteins which are responsible for electron transfer
in a wide spectrum of reactions including metabolic biotransformation of endogenous and …

Ethylhexyl diphenyl phosphate (EHDPP) is a common flame retardant and environmental
pollutant, exposing humans with endocrinal disrupting potentials. Its mutagenicity, especially …

Bisphenols (BPs) are environmental pollutants with relevant DNA damage in human
population; however, they are generally inactive in standard mutagenicity assays, possibly …

Species differences are among the main reasons for the high failure rate of preclinical
studies. A better awareness and understanding of these differences might help to improve …

Various upcoming techniques can be used in replacement of experiments requiring animal
sacrifice or products of animal sacrifice. In many instances these techniques provide more …