The adhesive interactions of cells with their environment through the integrin family of
transmembrane receptors have key roles in regulating multiple aspects of cellular …

ABSTRACT Funded by the National Institute of Allergy and Infectious Diseases, the Pat
hosystems R esource I ntegration C enter (PATRIC) is a genomics-centric relational …

In spite of a growing body of research and data, human ageing remains a poorly understood
process. Over 10 years ago we developed the Human Ageing Genomic Resources (HAGR) …

Circular RNAs are new players in regulation of post transcriptional gene expression. Animal
genomes express many circular RNAs from diverse genomic locations. A recent study has …

Previous investigations have combined transcriptional and genetic analyses in human cell
lines,,, but few have applied these techniques to human neural tissue,,,,. To gain a global …

Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

Long noncoding RNAs (lncRNAs) have been described in cell lines and various whole
tissues, but lncRNA analysis of development in vivo is limited. Here, we comprehensively …

The Drd2 gene, encoding the dopamine D 2 receptor (D2R), was recently indicated as a
potential target in the etiology of lowered sociability (ie, social withdrawal), a symptom of …

Protein-protein interactions (PPIs) are useful for understanding signaling cascades,
predicting protein function, associating proteins with disease and fathoming drug …

Background A deeper understanding of differences and similarities in transcriptional
regulation between species can uncover important information about gene functions and the …