Most therapies for treating sensorineural hearing loss are challenged by the delivery across
multiple tissue barriers to the hard-to-access anatomical location of the inner ear. In this …

The inner ear is sensitive to various infections of viral, bacterial, or fungal origin, which, if left
untreated, may lead to hearing loss or progress through the temporal bone and cause …

We prepared a new injectable thermogel to enhance the efficiency of inner ear delivery of
dexamethasone (DEX). Hexanoyl glycol chitosan (HGC) was synthesized and evaluated as …

Objectives Various animal models have been established and applied in hearing research.
In the exploration of novel cochlear implant developments, mainly rodents have been used …

Hearing loss, the most common human sensory defect worldwide, is a major public health
problem. About 70% of congenital forms and 25% of adult-onset forms of deafness are of …

Meniere's disease (MD) is a progressive inner ear disorder involving recurrent and
prolonged episodes or attacks of vertigo with associated symptoms, resulting in a …

Hearing impairment is the most common sensory disorder in humans, and yet hardly any
medications are licensed for the treatment of inner ear pathologies. Intricate …

Many hearing-impaired patients may significantly benefit from the Hybrid or electro-acoustic
stimulation (EAS) cochlear implant (CI). However, as much as 30-55% of CI recipients lose …

Hearing loss negatively impacts the well-being of millions of people worldwide. Systemic
delivery of ototherapeutics has limited efficacy due to severe systemic side effects and the …

Treating pathologies of the inner ear is a major challenge. To date, a wide range of
procedures exists for administering therapeutic agents to the inner ear, with varying degrees …