Major depressive disorder (MDD) is a common and complex mental disorder, that adversely
impacts an individual's quality of life, but its diagnosis and treatment are not accurately …

Despite numerous studies on the neurobiology of depression, the etiological and
pathophysiological mechanisms of this disorder remain poorly understood. A large number …

Depression is the most prevalent and debilitating mental disorder that affects a substantial
number of people globally, hindering all aspects of their lives and leading to a high number …

Adolescence is an important ontogenetic period that is characterized by behaviors such as
enhanced novelty-seeking, impulsivity, and reward preference, which can give rise to an …

Background Depression, as a prevalent and debilitating psychiatric disease, severely
decreases the life quality of individuals and brings heavy burdens to the whole society …

Major depressive disorder (MDD) is a common mental illness characterized by persistent
low mood and anhedonia, normally accompanied with cognitive impairment. Due to its rising …

Background Depression, one of the most common mental illnesses and mood disorder
syndromes, can seriously harm physical and mental health. As the pathophysiology of …

Depression is an overwhelming health concern, and many patients fail to optimally respond
to available standard therapies. Neuroplasticity and blood–brain barrier (BBB) integrity are …

Background Major Depressive Disorder (MDD) is a debilitating mental health condition with
complex etiology, and recent research has focused on pro-inflammatory cytokines and …

Patients diagnosed with inflammatory bowel disease (IBD) exhibit a notable prevalence of
psychiatric disorders, such as anxiety and depression. Nevertheless, the etiology of …