The pathophysiology of gestational diabetes mellitus
Gestational diabetes mellitus (GDM) is a serious pregnancy complication, in which women
without previously diagnosed diabetes develop chronic hyperglycemia during gestation. In …
without previously diagnosed diabetes develop chronic hyperglycemia during gestation. In …
Oxidative stress and diabetes: antioxidative strategies
Diabetes mellitus is one of the major public health problems worldwide. Considerable recent
evidence suggests that the cellular reduction-oxidation (redox) imbalance leads to oxidative …
evidence suggests that the cellular reduction-oxidation (redox) imbalance leads to oxidative …
Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus
Diabetes mellitus is characterized by the failure of insulin-secreting pancreatic β-cells (or β-
cell death) due to either autoimmunity (type 1 diabetes mellitus) or failure to compensate for …
cell death) due to either autoimmunity (type 1 diabetes mellitus) or failure to compensate for …
[HTML][HTML] From NASH to diabetes and from diabetes to NASH: mechanisms and treatment options
A Gastaldelli, K Cusi - JHEP reports, 2019 - Elsevier
The worldwide prevalence of non-alcoholic fatty liver disease (NAFLD) is estimated to have
reached 25% or more in adults. NAFLD is prevalent in obese individuals, but may also affect …
reached 25% or more in adults. NAFLD is prevalent in obese individuals, but may also affect …
Proteostasis of islet amyloid polypeptide: a molecular perspective of risk factors and protective strategies for type II diabetes
The possible link between hIAPP accumulation and β-cell death in diabetic patients has
inspired numerous studies focusing on amyloid structures and aggregation pathways of this …
inspired numerous studies focusing on amyloid structures and aggregation pathways of this …
Effect of glucagon‐like peptide‐1 receptor agonists on body weight in adults with obesity without diabetes mellitus—a systematic review and meta‐analysis of …
J Iqbal, HX Wu, N Hu, YH Zhou, L Li, F Xiao… - Obesity …, 2022 - Wiley Online Library
Clinical trials have investigated the weight loss effect of glucagon‐like peptide‐1 receptor
agonists (GLP‐1 RA) in adults with obesity without diabetes mellitus, but results for weight …
agonists (GLP‐1 RA) in adults with obesity without diabetes mellitus, but results for weight …
β Cell dysfunction during progression of metabolic syndrome to type 2 diabetes
In a society where physical activity is limited and food supply is abundant, metabolic
diseases are becoming a serious epidemic. Metabolic syndrome (MetS) represents a cluster …
diseases are becoming a serious epidemic. Metabolic syndrome (MetS) represents a cluster …
[HTML][HTML] Streptozotocin as a tool for induction of rat models of diabetes: A practical guide
Streptozotocin (STZ) is the most used diabetogenic chemical for creating rat models of type
1 and type 2 diabetes. Despite~ 60 years of using STZ in animal diabetes research, some …
1 and type 2 diabetes. Despite~ 60 years of using STZ in animal diabetes research, some …
Obesity as a disease
Obesity is a complex, chronic medical condition with a major negative impact on human
health. 1 Over the last 30 years, there has been an exponential growth in the prevalence of …
health. 1 Over the last 30 years, there has been an exponential growth in the prevalence of …
Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes …
AJ Garber, MJ Abrahamson, JI Barzilay, L Blonde… - Endocrine Practice, 2019 - Elsevier
ABSTRACT Abbreviations: A1C= hemoglobin A1C; AACE= American Association of Clinical
Endocrinologists; ACCORD= Action to Control Cardiovascular Risk in Diabetes; ACCORD …
Endocrinologists; ACCORD= Action to Control Cardiovascular Risk in Diabetes; ACCORD …