I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

A rapidly developing paradigm for modern health care is a proactive and individualized
response to patients' symptoms, combining precision diagnosis and personalized treatment …

Uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) is the most
bothersome phenotype of chronic rhinosinusitis; it is typically characterized by a type 2 …

Background Chronic rhinosinusitis with nasal polyps is frequently managed with endoscopic
sinus surgery (ESS). Prior studies describe individual clinical variables and eosinophil …

The enigmatic eosinophil has emerged as an exciting component of the immune system,
involved in a plethora of homeostatic and inflammatory responses. Substantial progress has …

Chronic rhinosinusitis (CRS) occurs in> 10% of the adult population in Europe and the USA
and can be differentiated into CRS without nasal polyps and CRS with nasal polyps …

Chronic rhinosinusitis (CRS) often is characterized by an eosinophilic inflammatory pattern,
nowadays referred to as type 2 inflammation, although the mucosal inflammation is …

Information for Category 1 CME Credit Credit can now be obtained, free for a limited time, by
reading the review articles in this issue. Please note the following instructions. Method of …

Abstract Coronavirus disease 2019 (COVID‐19), caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has been a rising international cause of …

Objective With the advent of new treatment options for Chronic Rhinosinusitis (CRS) comes
the ability for physicians to provide more individualized patient care. Physicians are now …