Clenbuterol and the horse revisited

CF Kearns, KH McKeever - The Veterinary Journal, 2009 - Elsevier
Clenbuterol is a β2-agonist and potent selective bronchodilator that is used to treat
bronchospasm in the horse. The drug is normally administered to horses orally as a syrup …

Biochemical Pharmacology: Polyamine‐mediated Heart Hypertrophy Induced by Clenbuterol in the Mouse

JC Cubria, R Reguera, R Balana‐Fouce… - Journal of pharmacy …, 1998 - Wiley Online Library
The use of β‐agonists as growth‐promoting agents in cattle could lead to toxic side‐effects
in man. One such effect is the accumulation of polyamines which seem to be implicated in …

Overexpression of antizyme in the hearts of transgenic mice prevents the isoprenaline-induced increase in cardiac ornithine decarboxylase activity and polyamines …

CA MACKINTOSH, DJ FEITH, LM SHANTZ… - Biochemical …, 2000 - portlandpress.com
Two lines of transgenic mice were produced with constitutive expression of antizyme-1 in the
heart, driven from the cardiac α-myosin heavy chain promoter. The use of engineered …

Effect of hindlimb suspension and clenbuterol treatment on polyamine levels in skeletal muscle

IK Abukhalaf, DA Von Deutsch, LE Wineski… - Pharmacology, 2002 - karger.com
Polyamines are unbiquitous, naturally occurring small aliphatic, polycationic, endogenous
compounds. They are involved in many cellular processes and may serve as secondary or …

Plasma and muscle polyamine levels in aerobically exercised rats treated with salbutamol

M Cepero, JC Cubria, R Reguera… - Journal of pharmacy …, 1998 - academic.oup.com
The induction of hypertrophy of cardiac and skeletal muscles has been studied after
treatment with two different salbutamol dosages, therapeutic and doping. Treatment of rats …

Muscle and serum changes with salbutamol administration in aerobically exercised rats

M Cepero, Y Perez-Pertejo, JC Cubrıa… - … and Physiology Part C …, 2000 - Elsevier
Treatment of experimental animals subjected to 90 days physical training programme plus
repeated doses of salbutamol, a β-adrenergic agonist, administered under two different …

Anabolic doping agents

DA von Deutsch, IK Abukhalaf, R Lapu-Bula - Handbook of Drug …, 2012 - Springer
This chapter discusses the different types of doping agents that have been used since the
pre-Christian era, such as hallucinogenic mushrooms and alcohol, up to those currently …

Changes in muscle proteins and spermidine content in response to unloading and clenbuterol treatment

DA Deutsch, IK Abukhalaf, LE Wineski… - Canadian journal of …, 2003 - cdnsciencepub.com
Anabolic agents such clenbuterol (Cb) are useful tools for probing the mechanisms by which
muscles respond to disuse. Cb was examined under different loading conditions with …

The induction of cardiac ornithine decarboxylase by β2‐adrenergic agents is associated with calcium channels and phosphorylation of ERK1/2

AJ López‐Contreras, ME de la Morena… - Journal of Cellular …, 2013 - Wiley Online Library
The role that the induction of cardiac ornithine decarboxylase (ODC), a key enzyme in
polyamine biosynthesis, by beta‐adrenergic agents may have in heart hypertrophy is a …

[引用][C] 克仑特罗药理作用的研究进展

张吟, 陈一农 - 海峡药学, 2002