Concussion as a multi-scale complex system: an interdisciplinary synthesis of current knowledge

ES Kenzie, EL Parks, ED Bigler, MM Lim… - Frontiers in …, 2017 - frontiersin.org
Traumatic brain injury (TBI) has been called “the most complicated disease of the most
complex organ of the body” and is an increasingly high-profile public health issue. Many …

Concussion and the autonomic nervous system: An introduction to the field and the results of a systematic review

JL Pertab, TL Merkley, AJ Cramond… - …, 2018 - content.iospress.com
BACKGROUND: Recent evidence suggests that autonomic nervous dysfunction may be one
of many potential factors contributing to persisting post-concussion symptoms. OBJECTIVE …

White matter changes in patients with mild traumatic brain injury: MRI perspective

PA Narayana - Concussion, 2017 - Future Medicine
This review focuses on white matter (WM) changes in mild traumatic brain injury (mTBI) as
assessed by multimodal MRI. All the peer reviewed publications on WM changes in mTBI …

Volumetric MRI findings in mild traumatic brain injury (mTBI) and neuropsychological outcome

ED Bigler - Neuropsychology Review, 2023 - Springer
Region of interest (ROI) volumetric assessment has become a standard technique in
quantitative neuroimaging. ROI volume is thought to represent a coarse proxy for making …

[HTML][HTML] White matter signal abnormalities in former National Football League players

ML Alosco, IK Koerte, Y Tripodis, M Mariani… - Alzheimer's & Dementia …, 2018 - Elsevier
Introduction Later-life brain alterations in former tackle football players are poorly
understood, particularly regarding their relationship with repetitive head impacts (RHIs) and …

[HTML][HTML] Systems biology, neuroimaging, neuropsychology, neuroconnectivity and traumatic brain injury

ED Bigler - Frontiers in systems neuroscience, 2016 - frontiersin.org
The patient who sustains a traumatic brain injury (TBI) typically undergoes neuroimaging
studies, usually in the form of computed tomography (CT) and magnetic resonance imaging …

Assessing pediatric mild traumatic brain injury and its recovery using resting-state magnetoencephalography source magnitude imaging and machine learning

MX Huang, A Angeles-Quinto, A Robb-Swan… - Journal of …, 2023 - liebertpub.com
The objectives of this machine-learning (ML) resting-state magnetoencephalography (rs-
MEG) study involving children with mild traumatic brain injury (mTBI) and orthopedic injury …

Increased glymphatic system activity in patients with mild traumatic brain injury

Z Dai, Z Yang, Z Li, M Li, H Sun, Z Zhuang… - Frontiers in …, 2023 - frontiersin.org
Purpose This study aims to investigate the glymphatic system activity changes in patients
with mild traumatic brain injury (mTBI), particularly in MRI-negative patients, using analysis …

Prevalence of potentially clinically significant magnetic resonance imaging findings in athletes with and without sport-related concussion

AP Klein, JE Tetzlaff, JM Bonis, LD Nelson… - Journal of …, 2019 - liebertpub.com
Previous studies have shown that mild traumatic brain injury (mTBI) can cause abnormalities
in clinically relevant magnetic resonance imaging (MRI) sequences. No large-scale study …

Structural neuroimaging in sport-related concussion

ED Bigler - International journal of psychophysiology, 2018 - Elsevier
Structural neuroimaging of athletes who have sustained a sports-related concussion (SRC)
can be viewed as either standard clinical imaging or with advanced neuroimaging methods …